Ginkgo biloba

Characteristics

A standardized extract of the plant leaves dvoulopastny Ginkgo (Ginkgo biloba). Contains flavonoglikozida, terpenolactona (ginkgolida and bilobalida) and other extractive substances.

Of drugs

Drugs, the properties, psihostimulirutee, improves cerebral blood circulation, antihypoxia, improves microcirculation, antiagregatine, reducing capillary permeability, venotonizirutee, force on improving blood circulation. Regulate metabolism in cells, the flow properties of blood and microcirculation, and the reaction vazomotorne blood vessels. Improves cerebral blood circulation and the supply of oxygen to the brain and glucose. Provides dozozawisimoe vazoregulirutee act stimulates a endotelialnogo relaksirutego factor expands small artery increases tone veins, regulating blood pressure. Ingibiruet fosfodiesterzu, resulting in the accumulation of cells gladkomyshechnykh arteriol Atmf, reduce muscle arteriol, including spazmirovannah and increased blood flow in microcirkulatornom course. Ingibiruet factor activate platelets, inhibits agregatia count and erythrocyte hinders tromboobrazovaniu allocation and improve tone muscles gladkomyshecna mediators. Decreases vascular permeability of the wall has expressed protivooterne Effects (the brain and peripheral tissues). And antigipoksicskimi, antioxidant properties. Prevents formation of free radicals and peroxide oxidation of lipids of cellular membranes, increases the number of normal and ATF accumulation in the cells, increase the utilization of oxygen and glucose, normalization mediator in the central nervous system. The experiment on animals increases neuronal survival in the face of the Gipoksii.vlijaet neiromediatorne processes in the central nervous system : stimulation of the release of presinapticakih terminaley and ingibiruet reverse takeover biogenic amines (norarenalina, release), increases sensitivity postsinapticakih muskarinovykh receptors for acetylcholine. Impact on ацетилхолинергическу ю system is nootropony, and �атехоламинергическу�� system-antidepressive Effect.sposobstvet improve cognitive function, improves memory and the ability to learn. Single admission regardless of the dose increases the power alfa-ritma, reduce power slow pace of EEG and latent period "cognitive component" evoked potentials. In Alzheimer's disease in a long-term therapy is stabilizing or weak positive effect on the human memory, attention, psychomotor functions, optimizing Bioelectrical activity of the brain contributes to the slow progression of Demention.okazavaet positive effect on human peripheral blood circulation : obliteriruuschem cattle lower limbs, mikroangiopatii diabetes, retinopathy and other conditions involving chronic ischemic peripheral tissues. In obliteriruuschem cattle lower limbs in a dose of 120-160 mg / day for 3-6 months adds up to a pain while walking. Decreases pronounced dizziness and increases Potentia.pri ingestion well absorbed, C_max achieved through 1.5 hour T_1/2 is 4.5 hours Malotoksicen.

Indications

Discirkulatornaya encephalopathy (consequences stroke, head trauma, aged age), manifested disorders attention and / or memory decline in intellectual abilities, alarm, fear, sleep disturbances; Dementia, incl. in Alzheimer's disease; to improve memory and attention for young people; neirosensorne disorders (dizziness, noise in the ears, hypoacousis) Hévíz degeneration yellow stains diabetic retinopathy; asthenic conditions : psychogenic, neurotic from traumatic brain impairment; Violations of peripheral blood circulation and circulation, including arteriopatii lower limbs, Reynaud syndrome.

Pregnancy and lactation

We do not recommend (not enough clinical experience).

Contraindications

Гиперчувствительност ь.

Side-Effects

Diarrhoeal disorders, headache, dizziness, allergic reactions.

Dosing and Administration

Inside, at the time of delivery. Dementia : 40-80 mg three times a day (120 mg / day). Astenicescoe disorder : 240 mg / sut. Other : 40 mg three times daily or 80 mg twice a day. The course of treatment is at least 8 weeks (average 3 months).

Literature

Vladimir Zakharov, Ahno NN The tanakana if there is a violation of brain and peripheral circulatory / / RMJ .- 2001 .- T. 9 N-15 - C. 645-649.

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