Pentagastrin

Chemical name

N-[(1,1-Диметилэтокси)ка��бонил]-L-аланил-L-трипт офил-L-метионил-L- альфа-аспартил-L-фенил аланинамид

Gross

C37-H49-N7-O9-S

Characteristics

Analogous gastrina-digestive hormone Trakta.bely jeltovato-bely or amorphous powder odourless. Virtually nerastvorim in water, very little is soluble in alcohol.

Of drugs

Drugs, the diagnostic. It stimulates the production of hydrochloric acid, pepsina and internal Kastla factor in the stomach. Increases secretion of pancreatic cancer, increases of the lower ulcers pouches, tip of antralnogo Division motoriku syndrome (directly affects the smooth musculature bowel), and motor activity of the large bowel. Increases retropoulshiyu slows stomach emptying and increases blood in his eye. Ingibiruet lost water and salts from lymph cancer. Is withdrawal of sodium and chloride with Mochoe.bystro rats after injecting, biotransformiroetsa in the liver. Report the news. T_1/2 least 10 Min.secretia activated in 10 minutes after injection, reaches its peak in 20-30 minutes and lasted 60-80 minutes.

Indications

Diagnostics secretion and the ability kislotoobrazoutei stomach functions, including anatidnykh gipersecrethornykh and conditions associated malignant anemia atroficski gastritam or malignant tumours stomach; The extent gipersecretii ulcer duodenal ulcer, post ulcers and tumours Zollinger-Ellison.

Contraindications

Hypersensitivity, circulatory insufficiency II stage, the heart rhythm expressed gipotenzia, saying disease stomach and duodenal ulcer in the process of being increased.

Side-Effects

Excessive salivation, nausea, abdominal pain, craving for urinating, vomiting, move in the abdomen, krovanistye protective allocation, hyperemia, tachycardia, short-term decline AD, dizziness, headache, weakness, fatigue, anxiety disorders, mood instability, impaired vision, frequent breathing, the feeling of gravity in the limbs, vomiting, pricking the fingers, allergic reactions.

Precautions

It should be borne in mind that in doses exceeding recommended may inhibition jeludocnuu secretion.

Dosing and Administration

P / to-6 µ g / kg

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