Iodamide

Chemical name

3-(Ацетиламино)-5-[(ацет��ламино)метил]-2,4,6-трий одбензойная acid (and in the form of meglumine or sodium salt)

Gross

C12-H11-I3-N2-O4

Characteristics

The white crystalline powder. It is soluble in water.

Of drugs

The drugs-rentgencontrastnoe. The visualization receptacles cavities and mochevyknoxiath ways in the X-ray study. After the on / in the circulates in sossoudistom line and out with the urine through glomeruliarna filtering and glands in renal bone.

Indications

G (diseases of the blood vessels, heart, kidneys, urinary tract, tumors internal organs, soft tissues and bones, obliteriruty endarteriit, cerebral, varicose veins thrombosis, gemangioma, injury limbs of suspected damage to the main receptacle), urografia (disorders of the kidneys and urinary tract).

Restrictions on the use of

Heavy damage parenhima liver and kidney diseases, hypertension under decompensation, Ray, active tuberculosis, a disease mielomnaya (multiple mieloma), a significant increase in blood coagulability.

Contraindications

Гиперчувствительност ь (including from other yodsoderjasim drugs), the shock collapse.

Side-Effects

Feelings heat, dizziness, nausea, vomiting, tachycardia, zianoz. Less increased slunootdelenia, slezotechenie, eritematosnye skin, urticaria, anaphylactoidnaya reaction and anaphylactic shock, zudaschie exantema. It is rarely bronhospazm, swelling Kwinke, arterial hypotension, kollaptoidnye state Already, fibrillace ventricular heart stops the heart, lung edema, neurological disorders (epileptiformnye seizures), pharmaceuticals syndrome red Lupus, Ray, bophlebitis.

Precautions

Large quantities of contrast substances are increasing stress on the heart, and their imposition of patients with serious coronary circulatory and heart failure should be carried out with caution.

Dosing and Administration

Yodamid-380 in peripheral suicide (flebografia, exkrethornaya urografia) 1 ml / kg (but not more than 100 ml) Quick 0,3-25 ml / s directly to the cavity of the heart, 30-50 ml; In / a (aortografia, arteriografia) 0.5-1 ml / kg; X-rays are 5-10 min after injection. For vnutripolostny a raise in izotonicescom solution of sodium chloride or 5% glucose to the 30% solution; Retrograno give the ureter 6-8 ml (X under visual control), in the bladder, 100-200 ml. For cerebral angiography apply only yodamid-300, being 6-10 ml Quick 5-10 ml / p

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