Directory Gematotropona funds Fibrinolitiki Zeliaza
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Zeliaza

See also Streptokinase

Roman name

Celyasum

Of drugs

Zeliaza activates contained in the blood fibrinoliticeski proferment (protein involved in the dissolution of blood bunch), plazminogen, which is emerging as a plazmin. Pronicast inside clot (of blood bunch), and is its dissolution.

Storage conditions

List B. The temperature of 2 ° C to 10 ° C.

Indications for use

Systemic and local arterial and brain venoznae (education bunch blood in the cup). The drug most effective when used during the first seven days of illness.

Dosing and Administration

Intravenous drip or vnutriarterialno. The contents of sealed dissolve 1-2 ml of the solvent (complete dissolution occurs within 1-2 minutes, the mists, muti, draught is not permitted). The solvent used reopoli-glukin, isotonic solution of sodium chloride, 5% glucose. After the complete dissolution of the contents of sealed injected into a bottle with one of the above solvents. Solution retains specific activity within 24 hours

Side-Effects

Rezorbtus fever (a sharp increase in body temperature associated with the arrival of a blood products clot). Possible reaction in the form of gipertermii (temperature increase), oznoba, headache, pain in the lumbar region, nausea caused by the presence of a heterogeneous product (foreign) protein.

Contraindications

Diseases and conditions predisposing to the uterus : diateza hemorrhagic (bleeding fever), ulcerative defeat gastrointestinal tract, severe sepsis (blood infection from microbes home purulent inflammation), haemorrhagic stroke (severe violation of cerebral circulation as a result of the collapse of the brain), pulmonary tuberculosis, AIDS with kavernoznam process active rheumatoid process, and other infections caused by the streptococcal; acute alcohol intoxication (alcohol poisoning), Early (up to 3 days.) posleoperazionny, the post-partum period, pregnancy. Persistent arterial hypertension (persistent rise in blood pressure). In severe forms of diabetes mellitus use zeliaza only for health reasons.

Form of

In sealed in liofilizirovannom form (powder, rehydration by freezing in a vacuum) to 250,000 ME, in a package 10 pieces.

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