Streptaza

Roman name

Streptase

The composition and the form of

1 bottle with liofilizirovannam powders for the preparation of injection solution contains streptokinaza 250,000, 750,000, or 1.5 million IU; in a Box 1, or 10 bottles.

Characteristics

Vsokoochischennaya streptokinase leachate from the culture fluid beta-gemoliticski flu Lensfield Group C.

Pharmacokinetics

T_1/2-23 min. Meta 48fe bolized by hydrolysis. Renal failure does not affect Cl Streptaza, liver, it slows down.

Clinical pharmacology

After Infusion fibrinoliticeski effect of a drug for a few hours, trombinovogo extension of time may be up to 24 hours due to the simultaneous reduction fibrinoguena and an increase in the number of circulating degradation products and fibrina fibrinoguena.

Indications

Acute myocardial infarction, thrombosis of deep veins, tromboembolia pulmonary artery and severe brain podostrae peripheral arteries, chronic disease occluzie arteries occluzie defeat receptacles central eye.

Contraindications

Hypersensitivity, internal bleeding, bloody diates, anaemia, renal and hepatic failure, erosivno-azwenne shock syndrome, menstrualnoe bleeding, the early stages of the disturbance of cerebral circulation, operations, the birth; Active tuberculosis, vnutricerepnae neoplasms, arterial hypertension, gipokoagulyatsia, hemorrhage, diabetic retinopathy predserdy blinking in the face of evil Mitral, bacterial endocardit, pregnancy (first 18 weeks).

Side-Effects

Fever, chills, headache, gastrointestinal violations generalized exantema, artralgia, mialgia, arterial hypotension, tachycardia, aetiology, bleeding, allergic reactions (including anaphylactic shock).

Patient interaction

When combined with a antikoagulyantami, antiagregantami increased risk of bleeding.

Storage conditions

List B. The temperature 2-25 ° C

Shelf life

3 years

The registration

012883/01-2001

Directory → Gematotropona funds → Fibrinolitiki → Streptaza