Aminomethylbenzoic acid

Chemical name

1-Карбокси-4-аминомети��бензол

Gross

C8-H9-N-O2

Characteristics

The white crystalline powder and odourless, it is difficult soluble in water.

Of drugs

The drugs-antifibrinoliticescoe, gemostaticescoe. Ingibiruet Activators plazminoguena and plazmina hampered fibrinoliz. Is stabilization fibrina and his deposition in sossoudistom lines indirectly induces agregatia and leukocyte adhesion and erythrocyte.

Indications

Bleeding from giperfibrinolizom : uterine, lung, kidney, perioperaie; Gipokoagulyatini in phase Dvs-sindroma with cirrhosis of the liver, ulcers stomach and duodenal ulcers, gemorragicescom syndrome тромбоцитопеническог о origin.

Restrictions on the use of

Breast-feeding.

Pregnancy and lactation

Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.

Contraindications

Trombofilicescie state accompanied by the development and trombozov tromboamboliy, giperkoagulyazionnaya phase Dvs-sindroma, heavy forms of coronary heart disease or brain, chronic renal failure, pregnancy.

Side-Effects

Vertigo, hypertension or gipotenzia (including ortostaticescuu), nausea, vomiting, diarrhoea, katarale phenomenon of the upper respiratory tract.

Precautions

Mandatory regular koagulogramma record. There must be adequate fluid consumption and monitor the adequacy diureza.

Dosing and Administration

Inside, 100-200 mg 3-4 times a day. In systemic bleeding, Dvs-sindrome in / in the 50-100 mg or / m 100 mg. Further dose adjusted individually.

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