Fibrinogen

Roman name

Fibrinogenum

Of drugs

It is a natural component of the blood. Moving fibrinoguena in fibrin unfolding under the influence of 821-828, the final stage of the process of blood clotting - education bunch. Fibrinogen used as a gemostaticski (кровоостанавливающе��о) funds derived from the blood plasma of donors.

Indications for use

Fibrinogen applied to hypothetical and afibrinogenemia (with a reduced fibrinoguena content in the blood and congenital absence fibrinoguena environments with high krovotochivostyu), in artistic methods trauma, surgical, oncological practice massive artistic methods in obstetric and gynaecological practice (prejde.wremennaya detachment of the placenta, childbirth against hypothetical and afibrinogenemia, etc.) and other artistic methods, associated with a lower content fibrinoguena in blood.

Dosing and Administration

Misleading solution fibrinoguena suicide in the system to the infusion drip filter. The drug mixtures ex tempore (to use) s water for injection, heated to a temperature of 25 to 35 C; Water quantity indicated on the label (the vial). Solution should be used no later than one hour after cooking. Dose of drug depends on the evidence, ranging from 0.8 to 8.0 g or more. The average dose usually sostashhaet 2-4 and

Contraindications

Fibrinogen is not suitable for predtromboticeskih conditions (conditions prior to hardening vessel sgustkom blood), trombozah (Education bunch blood in the cup) of different etiology (cause), elevated blood coagulability myocardial infarct.

Form of

In hermetically ukuporennah glass bottle capacity of 250 or 500 ml, respectively containing 1 g (1 0.2 g), or 2 g (1.9 0.1 g) koaguliruemogo protein (fibrinoguena). By flaconu attached to the infusion to the filter. The preparation should grows for a period of not more than 10 minutes in the specified on the label of water, heated up to 25 or 35 "C; PH (a measure of the acid) solution from 6,5-7,4. Solution opalestiruet (diffuse light).

Storage conditions

At temperatures of 2 to 10 ° C in a dry, the dark spot. Storage products at temperatures above 10 ° C is denaturatia (loss of a specific activity) fibrinoguena.

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