Immunat

Roman name

Immunate #

The composition and the form of

1 bottle with liofilizirovannam powders for the preparation of injection solution includes factors such as blood clotting VIII 250, 500 or 1,000 IU, complete with water for injection in vials of 5 and 10 ml, and the set of supplies for the plants and the introduction of (syringes and needles); in a box 21.90.

Of drugs

Gemostaticescoe. Fills deficit endogenous factor out VIII in the blood plasma, normalizes gemokoagulyatia in patients with the deficit.

Indications

Bleeding from congenital or acquired deficiency factor VIII : haemophilia A, ingibitornaya form of hemophilia A, acquired deficit factor VIII related to the spontaneous emergence of the inhibitor (treatment and prevention), a disease Villebranda insufficient factor VIII.

Contraindications

Гиперчувствительност ь.

Side-Effects

Gemoliz, education in the blood antibody inhibiting factor VIII allergic reactions.

Specific guidance

For Infusion using single system with adequate filter. The solution was to be spent quickly and not reused.

Precautions

Not to be confused with other drugs. When pregnancy and breast-feeding is used only in case of dire need. When signs of allergy treatment must stop and start antigistaminnuu or protivosokovu therapy. Appointment of high doses especially requiring mandatory monitoring of patients with blood groups A, B and AB to be able to recognize hemolysis.

Dosing and Administration

In / in, or struino drip (speed of not more than 2 ml / min), dissolved 250-500 IU in 5 mL and 1,000 IU in 10 ml of water for injection immediately before introduction. To calculate the effective therapeutic dose, the level of factor VIII in plasma, and use formula-dose (IU) = weight (kg) x desired increase factor VIII (%) x 0.5. Misleading intervals 8-12 hours; With severe hemophilia A is 10-50 IU / kg at intervals of 2-3 days, with ingibitorna form of hemophilia dosing expect individually on the basis of coagulation tests; For the prevention of bleeding in surgical operations, for one hour before the operation, in the event of a major interference to the operation and every 8 h post first day.

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