Konin 80

Roman name

Konyne 80

The composition and the form of

1 bottle with liofilizirovannam powders for the preparation of injection solution contains factor IX complex 500, or 1,000 IU, as well as plasma koagulyaie factors II and X, few factor VII (prokonvertin), together with the solvent in sealed for 20 or 40 ml respectively, as well as with bilateral and needle igla-filtrom.

Of drugs

Gemostaticescoe. Fills deficit to a number of factors such as blood clotting (IX, X, II, VII).

Farmakodinamika

Increases level of factor IX, as well as some other vitamin K-zawisimah coagulation factors (II, X, VII) in plasma and restores gemostaz patients with a deficit factor IX (for injuries or surgery).

Indications

Hemophilia B in children and adults with a place or threatening bleeding; Bleeding in the face of anti kumarinovykh; Bleeding in hemophilia A in patients with inhibitors factor VIII.

Contraindications

None.

Side-Effects

The sense of heat, oznoba, tidal blood tingling sensation, headache pain. Seldom-posleoperazionny thrombosis.

Patient interaction

Together with the application эпсилон-аминокапроно��ой acid increases the risk of thrombosis.

Precautions

It should not be applied to individuals predisposed to thrombosis, as well as liver diseases in which there is suspicion vnutrisosudistoi coagulation and fibrinolysis. With long-term therapy constant monitoring of factors II, IX and X in the blood of patients. When pregnancy is used only in cases of extreme necessity.

Dosing and Administration

Misleading in / in supporting dose 10 to 20 IU / kg body weight per day. In patients with hemophilia A dose of 75 IU / kg; If necessary, re-establish within 12 hours

Storage conditions

por.liof.d / in. : List B. The temperature of 2-8 ° C (not freezing). When concentrate product can be stored up to one month at a temperature of no higher than 25 ° C.

Shelf life

por.liof.d / in. : 2 grams.

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