Octavi

Roman name

Octavi #

The composition and the form of

1 bottle with 510-770 mg liofilizirovannogo powder for the preparation of injection solution contains fraction of plasma factor rich blood clotting VIII providing its activity equal to 250 IU (with a total protein content of 1-5 mg; Octavi 250), 500 IU (protein 2-10 mg; Octavi 500), or 1,000 IU (protein 4-20 mg; Octavi 1000); Together with the solvent (water for injection), in bottles of 10 ml. The package also has one single injection of 10 ml, one needle with two ends, one needle passes, 1 kit bags and 2 rollers, soaked in alcohol.

Characteristics

Liofilizirovanny human factor blood clotting VIII.

Of drugs

Gemostaticescoe. Fills deficit reduction factor VIII blood.

Indications

Under factors such as blood clotting VIII, including haemophilia A; Violations hemostasis caused by antibodies to factor VIII.

Contraindications

None.

Side-Effects

Increased body temperature, developing antibodies to factor VIII, gipervolemia, gemoliz, reduced resistance to infectious diseases, allergies, including anaphylacticskie reaction.

Dosing and Administration

In / in slowly (tentatively qualified in the attached solvent). And the dose rate set individually. In calculating the dose to take into account that changing one factor VIII per kg body weight increases the level of factor VIII in the blood by 1-2% and the 12-hour activity factor VIII is reduced by 15%. In gemorragiah in joints, muscles and small artistic methods in the treatment of factor VIII increase by 10-20% (treatment 2 days); In the artistic methods in the oral cavity, removing teeth, a level of operations should not be less than 30% (treatment five days); in the gastrointestinal artistic methods fall in the level of factor VIII may be below 50% (treatment from 10 to 14 days); in complex transactions or intracranial krovoislianiah below 60% (treated 2-3 weeks). To prevent prolonged bleeding with severe hemophilia A being 12-25 IU / kg every 2-3 days (if necessary increase the dose and reduce intervals).

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