Epoetin omega

Chemical name

омега-(1-165)-Эритропоэт��н (gennoingenernyi); glikoprotein consisting of 165 amino acids

Of drugs

The drugs-gemopoeticescoe, eritropoeticescoe. Is the normalization of the number of red blood and the content of the hemoglobin.

Indications

Anaemia in the face of chronic kidney failure.

Restrictions on the use of

Hypersensitivity, arterial hypertension, pregnancy (I term), breast-feeding (at the end of treatment), children's age.

Side-Effects

Hyper or gipotenzia, tachycardia, stenocardia, thrombosis, giperkaliemia, grippopodobnaya symptoms, swelling, fatigue, convulsions gastrocnemius muscles, bronchitis, diarrhoea, prurit, anaphylactic shock.

Overdosing

Symptoms : gematokrita increase, the level of hemoglobin, the blood viscosity, hypertension, Tromboz.lechenie : cigarette and / or antikoagulyazionnaya therapy (in the face of the Erythropoietin).

Precautions

Be wary appoint the disease, convulsions and amnesia, in the II and III trimestrah pregnancy (only on the strict condition and in the lowest dose). At least 1-2 times a week should be monitoring levels of hemoglobin and gematokrita, in potassium, creatinine and others in the cell. The therapy of patients with brain once a month testing the coagulation of blood. Before treatment should be deleted factors that can reduce the effect of : vitamin B_12 and folic acid, aluminum poisoning, infections, therapy or korticosteroidami immunodepressantami.

Dosing and Administration

P / to the in / in, starting with 20 to 50 IU / kg three times a week, with a gradual increase in dose or frequency of issuance before the impact. Beyond haemoglobin levels to 12 g / m and gematokrita-35 on. % Dose reduction or no treatment. If there Effect dose increase to 40 to 55 IU / kg three times a week for two weeks, if necessary, until 60-75 IU / kg The course continues until the level gematokrita (35 vol. %) And hemoglobin (12 g / m); Total weekly dose should not exceed 225 IU / kg supporting-60 IU / kg per week for 2-3 reception.

Directory → Gematotropona funds → Amphetamine gemopoaiza → Epoetin omega