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Eritrostim injection

See also Epoetin beta

Roman name

Erythrostimum pro injectionibus

The composition and the form of

1 ampoule containing solution for injection contains recombinant beta epoetina 500, 2,000, 3,000, 4,000 or 10,000 IU and RNA albumin rights physiological natriy-zitratne buffer; USD in 1 ml, in a box 10 vials.

Of drugs

Eritropoeticescoe. Education stimulates cells contributes to the terminal differencirovke eritroidnykh cells.

Indications

The Erythropoietin, эритропоэтинзависима я anemia in patients with chronic renal insufficiency in gemodialise, anaemia in gemoblastozah, revmatoidnom arthritis, the Khabarovsk and people after chemotherapy, the newborn and premature babies; Anemia caused by radiation injury. Enlisting eritropoaiza in preparation for the handyman (prevention severe anemia, a decrease of blood).

Pregnancy and lactation

Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.

Contraindications

Hypersensitivity; Necorrigiruemaya arterial hypertension, epileptiformnye status, pregnancy, breast-feeding.

Side-Effects

The AD dializatora thrombosis or vascular access (shunt, VVF), grippopodobnyy syndrome, giperkaliemia, giperfosfatemia.

Precautions

Be wary when appoint trombozitoze, epileptiformnah states, hypertensive disease, hypersensitivity to albuminam blood.

Dosing and Administration

In / in slowly (at least 2 minutes), or c / GMT Initial dose-50 IU / kg three times a week. When the gematokrita less than 0.5% per week, increasing the dose of 25 IU / kg every 4 weeks. The maximum dose is not more than 200 IU / kg three times a week. After reaching the level of gematokrita 30-35%, and drop from 10 to 12%, last dose reduced by 50%. In order to maintain the achieved level gematokrita and hemoglobin dose picked individually.

Storage conditions

r-r d / in. : In dry the dark place at a temperature of 2-8 ° C

Shelf life

r-r d / in. : 2 grams.

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