Lakomax

Roman name

Leucomax

Overdosing

About accidental overdose Lakomaxa has been reported so far. However, the number of patients receiving the drug in doses that constituted 20 or 30 µ g / kg / day, there tachycardia, arterial gipotenzia and grippopodobnyy syndrome. After the symptomatic treatment of these symptoms quickly corrected.

Storage conditions

List B. sterilized lakomaxa powder in a glass vial type 1 with a lid or butilirovannogo galobutilirovannogo rubber and aluminium seals stable for a period of 24 months at a temperature +2- + S ° C, protection from the light.

Shelf life

The registration

008991

Of drugs

Lakomax is a water-soluble protein neglikolizirovanny. It consists of 127 amino acids, the molecular weight of 14,447 dalton contains izolitzin in regulation 100. Most pathogenic Escherichia coli, nesushim obtained through genetic engineering plazmidu containing gene гранулоцитарно-макро��агального �олониестимулирующег�� factor rights.

Dosing and Administration

Lakomax be applied under the supervision of a physician with experience in treating the disease, in which a product. The first dose lakomaxa should be imposed by ensuring careful medical observation of patients. Doses set in the light of evidence. The maximum daily dose of 10 µ g / kg

Side-Effects

Nausea, vomiting, anorexia (lack of appetite), diarrhoea (diarrhea), there are stomatitis (inflammation of mucous membranes of the oral cavity), pain in the abdomen; Convulsions, mialgii (muscular pain), a sense of fatigue, asthenic phenomenon (weak), there are headaches, dizziness, pareza (decrease forces and / or amplitude movements); Rarely sputannosti consciousness raising vnutricerepnogo pressure of cerebral circulation; Dyspnoea, rarely ekssoudativei pleurisy (inflammation of the lung membrane accompanied solution tissue rich in protein otdelemy); rarely arterial hypotension (low blood pressure), fainting, the disruptions to the heart, heart. failure, swelling lungs, increased capillary permeability, peripheral oedema, ekssoudativei pericardit (inflammation okoloserdecna bags accompanied solution tissue rich in protein otdelemy). In developing plevrita and / or pericardita lakomax should be abolished. There rashes, itching; Pain at the subcutaneous injection of the drug. From the laboratory of the most frequently mentioned decrease in the number of platelets, hemoglobin and albumin levels of serum. It has been more absolute and relative Eosinophils content in the blood. Rarely are allergic reactions in the form of bronchospasm (a sharp narrow clearance bronchi), pulmonary angioneuroticeski, anaphylacticski shock. When allergic reactions lakomax should be lifted immediately, and shall not apply. Often there fever (a sharp increase in body temperature), the pain in the bones. There nonspecific pain in the chest, increased sweating.

Contraindications

Hypersensitivity to the drug.

Form of

Dry liofilizirovanny (dried by the freeze in a vacuum) powder for injection in vials containing 50 g (0.55 h106 IU) ; 150 g (1.67 h106 IU) ; 300 g (3.33 h106 IU) ; 400 g (4.44 h106 IU) ; 500 g (5.55 h106 IU) Or 700 µ g (7.77 h106 IU) .

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