Maltofer

Roman name

Maltofer #

The composition and the form of

1 USD 2 ml solution for injection contains elemental iron 100 mg; in the box five vials.

Of drugs

Protivoanemicescoe.

Pharmacokinetics

After the / m introducing into the bloodstream through the lymphatic system. C_max achieved within 24 hours In ретикулоэндотелиальн ой the split of the iron hydroxide and polimaltozu (metabolised by oxidation). The blood iron contact transferrinom in tissues stored in the ferritina, in the marrow included in the trailer and used in the process eritropoaiza.

Indications

Iron deficiency in inefficiency or inability to receive oral iron products (including in patients with gastrointestinal diseases and suffering malabsorbziei).

Pregnancy and lactation

Contraindicated in the first trimester of pregnancy may in Groups II and III триместрах.Беременно��ть Category C : a pilot study of reproduction, as well as controlled studies in pregnant women with the drug at all. Thus product into sealed can be used only in cases where the outcome of treatment exceeds potential risk to Ploda.v small quantities continued iron from the complex polimaltosny can enter breast milk, but it is unlikely an undesirable effects on breastfeeding children.

Contraindications

Hypersensitivity; Anemia not related to iron deficiency (Hemolytic, megaloblastnaya caused by vitamin B_12); Violations eritropoaiza, gipoplasia bone marrow; Excess iron in the body (hemochromatosis, gemosideros); The recycling of iron (sideroahrestical anaemia, thalassaemia, anaemia lead, extended porphyria skin); Osler syndrome - Randu-Weber; Chronic polyarthritis; Bronchial asthma; infectious diseases in the kidneys acute stage; giperparatireoz uncontrolled; decompensirovanny cirrhosis; infectious hepatitis.

Side-Effects

On rare occasions, there pain in the joints, in lymph nodes, fever, headache, malaise, stomach disorders, nausea, vomiting, we treat simptomaticeski. Very rarely can develop allergic or anaphylacticskie reaction. Is the technology could lead to paint skin, the emergence of the pain, inflammation at the injection.

Specific guidance

You can only use the screen intact. When forming sludge solution is not suitable for use. After opening screen solution should be imposed immediately. Not to be confused with other therapeutic drugs.

Patient interaction

ACE inhibitors increase the systemic effects. It should not be used in conjunction with oral iron therapy (reduced intake of iron from the digestive tract).

Precautions

Designed for the / m introduction. Be wary appoint patients with liver and kidney disease, asthma, cardiovascular disease and allergies заболеваниями.Введен��е children under four months of age is not recommended due to the lack of Opata.v case of a moderately expressed allergic reactions recommended antihistamines drugs in the development of heavy anaphylacticescoy reaction, immediate adrenalin.

Dosing and Administration

V / m. The first application should be intramuscular test : adult-1/4-G doses (25-50 mg iron), children 1 / 2 daily doses; In the absence of adverse events within 15 minutes of entering the remainder of the initial dose. Dosage is selected and calculated individually. The maximum tolerable daily intake : children weighing up to 5 kg - 0.5 mL (25 mg iron), from 5 to 10 kg-1 ml (50 mg iron); Adults : 4 ml (200 mg iron). If the response from the haematological parameters (for example, an increase in haemoglobin levels of 0.1 g / m / day) is in 1-2 weeks, the initial diagnosis should be reconsidered. The total dose of drug treatment should not exceed the calculated number Ampul.tehnika injections (see figures) : injection technique is critical. As a result of the misuse of drugs may be pain and staining the skin at the injection. Described below is ventro-agodicna injections recommended instead accepted in the upper outer quadrant of a large gluteus : a) The length of the needle must be at least 5-6 Proswet see needles should not be too broad. For children, as well as adults with a body mass, needles should be shorter and toneshe.b) In accordance with the recommendations Hochstetter, a drug is defined as follows (see Figure 1) : from the spinal column at a level consistent with пояснично-подвздошно��у coupling, the snap A. If the patient is on the right side, put the average finger of the left hand at the point A. Leave index finger of the average so that it was under the line of iliac crest at the point B. Triangle, located between proksimalnami phalanges, middle and index fingers is the injection (see Figure 2). Tools cleaned normal metodom.c) Before a needle, and then slide the skin by about 2 cm (see Figure 3) to a closed channel penetration of the removal of the needle. This prevents the penetration of the solution imposed in the subcutaneous tissue and fat koji.d) Place the needle vertically to the surface of the skin, at a sharp angle to the iliac joints than to the hip joint (see Figure 4). E) After the injections slowly remove the needle and adjust your skin station adjacent to the site of injections, for a period of five min.f) After injecting the patient should move.

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