Gemohes 10%

Roman name

Hemohes # 10%

The composition and the form of

1,000 ml for infusions contain поли(О-2-гидроксиэтил)��рахмала (with a molecular weight of 200,000) 60 or 100 g and sodium chloride 9 g (ions sodium 154 mmol / l, chlorine ions 154 mmol / l; pH 4-7; theoretical osmolarity 310 Mosm / l); in polyethylene bottles of 500 ml, in a box 10 pcs. (Gemohes 6%).

Of drugs

Plazmozameshchatee. Normalizes or more circulating plasma volume at 3-4 hours; Improves the flow properties of blood and microcirculation. 6% solution is a isoonkoticski and 10% giperonkoticski.

Pharmacokinetics

Gidroxiatilkrahmal for some time partly stored in the cells ретикулоэндотелиальн ой system. Destroyed savorotocna Digest, and presented almost entirely by the kidneys.

Indications

Prevention and treatment gipovolemii and shock (including in the pre and therapeutic gemodiluci).

Pregnancy and lactation

Only for health reasons.

Contraindications

Гиперчувствительност ь to krahmalu, gipergidratation, gipervolemia, severe heart failure, kidney failure, accompanied by oliguriei or anuriei, heavy human blood coagulability after birth and the age of child (up to 12 years).

Side-Effects

Anaphylacticskie reactions of varying degrees of severity, skin rashes, red face and the neck; Rarely is a substantial increase in blood pressure, shock, cause respiratory and heart problems.

Specific guidance

The gematokrita 25% or hemoglobin concentration 100 g / L in patients not suffering from heart or lung failure, is the lower limit for the appointment of colloidal objemozameshchath liquids. It should be borne in mind that Gemohes not reimburse proteins in plazma or krovopoteriah.

Precautions

In a caution to patients with suspected acute lack of cerebral circulation in human blood coagulability heart, lung and kidney failure, chronic liver diseases.

Dosing and Administration

In / in, drip. The dosage, and duration of the speed depends on the severity and krovopoteri gipovolemii. It should be borne in mind the possibility of overloading zirkulatorna by speeding the introduction or doses. For early detection of анафилактической/ана��илактоидной first reaction 20-30 ml should be introduced slowly and under the supervision of Vracha.maximalnaya daily dose of 2 g gidroxiatilkrahmala 1 kg body weight (equivalent to Gemohes 6% 33 ml / kg / day, or 2500 ml / day for patients weighing 75 kg and Gemohes 10%, 20 ml / kg / day, or 1500 ml / day �оответственно).Макси��альная the speed depends on the clinical situation. Patients with acute haemorrhagic shock drug can be injected with up to 20 ml / kg / hour (equivalent to 0.33 ml / kg / min). In critical situations, 500 ml of quick infusions (pressure). With the drug under pressure from the air should be removed from the bottle before the start of the drug, otherwise possible risk of air embolism at the time Wvedenia.neobhodim control vodno-elektrolitnogo balance oosbenno in gipernatriemii, ks and renal failure (control whey creatinine). If any blood coagulability and chronic liver disease, there is a need to control the size and RNA albumin. In connection with the possibility of an allergic (анафилактических/ана филактоидных) reactions required monitoring of patients.

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