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Finast

See also Finasteride

Roman name

Finast

Pharmacokinetics

After intake of rapidly absorbed from the digestive tract, bioavailability is about 80% (does not depend on the meals). C_max plasma achieved in 1-2 hours after oral reception, tying the plasma protein is about 90%. Metabolised in the liver, appears in the form of metabolites in urine and Kalom.t_1/2 in patients over the age of 60 is 6900, in patients over 70 years of age can be prolonged until 8 pm

Farmakodinamika

Decreases of prostate cancer increases the maximum speed of the outflow of urine and reduces symptoms of this giperplaziei; Reduces the risk of severe delays urine and the resulting likelihood surgery.

Clinical pharmacology

Duration of therapy to evaluate its effectiveness should not be less than six months. Approximately 50% of patients disappearance of clinical symptoms occurred in the treatment for 12 months.

Indications

Safe giperplazia prostate gland.

Contraindications

Hypersensitivity, obstructive uropatia, child.

Side-Effects

Allergic reactions ginekomastia, impotence, reduced libido, a decrease of volume (frequency of side effects does not exceed 3-4% and declined treatment). In some cases, there had been an improvement in the LTG, and opened testosterone approximately 10% (but they remained within normal limits).

Specific guidance

A high volume of residual urine and / or sharply reduced current urine should be aware of obstructive uropathy.

Precautions

Prior to the start of treatment should be deleted disease simulirute good giperplaziu prostate cancer (prostate infection, cancer prostate, the urethra strictora, gipotoniceski bladder and changes from the mochevforodaschei system associated with certain diseases nervous system). Be wary appoint patients violations of the Pecheni.periodiceski in therapy it is necessary to examine patients to exclude their prostate cancer (as in the application finasterida there has been a decline �ростат-специфическог о antigen-by 41 and 48%, respectively, by 6 and 12 months since the start of therapy). Women of childbearing age and pregnant women should avoid contact with the tablets crashed preparation, in view of the development of the genital organs of embryos male.

Storage conditions

List B. In a dry, the dark place at a temperature of no higher than 25 ° C

Shelf life

2

The registration

014580/01-2002

The drug forms

White round dvoyakovpuklae pills Film-coated with the Rx symbol on one side and smooth on the other hand; An Matochkin-white, or almost white mass.

All products of this group

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