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Nemestran

See also Gestrinone

Roman name

Nemestran

The composition and the form of

1 capsule contains gestrinon 2.5 mg; in blistere 8 pcs. , in the box one blister.

Pharmacokinetics

After intake of a single dose of 2.5 mg C_max achieved in 2 hours Sustainable concentration during the second admission to the third day. Cumulation withdrawal marked. T_1/2-27 p.m. Write 40-45% of the urine and 35% of the faeces.

Indications

Endometriosis (including oslojnenny infertility).

Contraindications

Heavy forms of heart, kidney or liver failure, pregnancy, lactation period, and the child aged age.

Side-Effects

Krovanistye separated from the vagina, skin, palliative whose fluid in the body, adding body mass index, girsutizm, change of voice, headache, tides, anxiety, depression, convulsions, a change of appetite, tranzithornoe increased liver transaminaz, changing libido, a decrease of mammary glands.

Patient interaction

Effect induktora reduce oxidation mikrosomalnogo (противоэпилептическ��е means rifampicin); incompatible with oral contraceptives.

Dosing and Administration

Inside, and 1 caps. (2.5 mg) twice a week for 6 months; first capsule taking first day of menstruation, the second on the 4th day, and then take on the same two days of the week over the course of treatment.

Storage conditions

B. List in a dry, cool, the dark spot

Shelf life

3 years

The registration

008707

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