Allylestrenol

Chemical name

(17бета)-17-(2-Пропенил)эс тр-4-ен-17-ол

Gross

C21-H32-O

Characteristics

Oral gestagenny product.

Of drugs

The drugs-progestagennoe. Does secretornuu phase cyclic changes endometrium and creating conditions for the development of eggs oplodotvorennogo reduces Oxytocics activity and sensitivity to oksitotino Oxytocics. Activates a atinusov mammary glands. Increases stocks fat. Has accumulation of liver glycogen and increases the utilization of glucose. Increases an adrenal Aldosteron.horosho absorbed by ingestion, metabolised in the liver, kidneys displayed.

Indications

Usual and threatening abortion, the threat of premature births.

Restrictions on the use of

Inflammatory kidney disease, chronic heart failure, lower tolerance to glukoze.

Pregnancy and lactation

During pregnancy shall be shown. Contraindicated during breast-feeding.

Contraindications

Hypersensitivity, violations of the liver, AIDS, 12:00 Johnson, fell syndrome, throm, embolic complications of cerebral circulation, mammary tumors and genital glands, toxaemia or herpes, incl. in the history.

Side-Effects

Diarrhoeal phenomenon headache whose fluid in the body, galactorea, induced mammary glands, throm, tromboembolia, acne, increased body mass index, holetsatical jaundice, hyperthermia, insomnia or drowsiness, depression.

Patient interaction

Inductive mikrosomalnogo oxidation reduces efficiency.

Precautions

Against the backdrop of diabetes requires systematic monitoring blood glucose (reduced tolerance to glukoze).

Dosing and Administration

Inside. When threatened miscarriage, 5 mg three times a day (but not more than 20 mg) to the disappearance of the symptoms; Familiar with the abortion-to 5 mg twice a day for a period of not less than one month after the critical period the dose can be reduced and for the 15 days before the reception. In threatening premature birth dose and duration of the case.

Directory → Hormones and their antagonists → Estrogens, gestagena; Their homologues and antagonists → Allylestrenol