Directory Hormones and their antagonists Estrogens, gestagena; Their homologues and antagonists Anteovin
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Anteovin

See also Exemestane

Roman name

Anteovin

The composition and the form of

1 tablet white contains levonorgestrel and etinilestradiola to 0.05 mg. 1 tablet pink levonorgestrel contains 0.125 mg and 0.05 etinilestradiola mg; conwalute in 21 pcs. , in box 3 conwaluta.

Pharmacokinetics

The ingestion of both rapidly and completely absorbed from the digestive tract. C_max achieved through 2 (levonorgestrel) and 1.5 hrs (levonorgestrel). Slowly metabolised in the liver, the main metabolite of levonorgestrel - 3-5-тетрагидроноргестр ел. T_1/2 - 2-7 pm Return with urine and faeces : levonorgestrel-60% and 40%, ethinylestradiol-40% and 60%. Active components infiltrating breast milk.

Indications

Contraception, functional menstrual irregularities (including pain, dismenorea).

Pregnancy and lactation

Contraindicated.

Contraindications

Heavy kidney disease, the syndrome 12:00-Johnson, fell syndrome expressed cardiovascular and cerebrovascular disease (including in history), severe arterial hypertension expressed diabetes, porphyria, hemostasis violations, violations of lipid exchange, liver cancer, breast cancer or endometrium, bleeding from the vagina unclear etiology, otoscleros, idiopathic severe jaundice, or skin itch during pregnancy in history.

Side-Effects

Diarrhoeal phenomenon, nausea, увеличение/уменьшени�� body mass index, bloating mammary glands, changing face, krovanistye separated from the vagina, headaches, fatigue, convulsions in the gastrocnemius muscles, skin rashes.

Specific guidance

Reliable contragestive effect develops only in the second round of admission tablets. In the case of regular admission contraceptive effect persists at the time the seven-day break. If regular admission allowed, it should be as soon as possible to take the pill, but braking moment can not be considered sufficient if the two methods table has been more than 36 hours In the three months prior to the pregnancy should be lifted product and move to another (negormonalny) method.

Patient interaction

Inductive mikrosomalnogo oxidation (rifampicin, derivatives phenobarbital, sulfanilamida, phenytoin, derivatives pirazolona, antibiotics, broad-spectrum) reduces efficiency.

Storage conditions

List B. In a dry, the dark spot.

Shelf life

5 years

The registration

014885/01-2003

Of drugs

Bifazny psroralny (used in the mouth) contragestive hormonal preparation delaying ovulation (the mature egg from the ovary).

Indications for use

Preventing pregnancy.

Dosing and Administration

Inside one tablet a day, preferably evening with the 5th day from the beginning of menstruation for 21 days before departure date, after which again within 21 days to 1 tablet a day, it is contraception. Initially <for 11 days) were 11 white tablets (1 tablet contains 0.05 mg levonorgestrel and 0.05 mg etinilestradiola), and then 10 pink (0.125 mg levonorgestrel and 0.05 mg etinilestradiola). The interval between admission tablets should not exceed 36 hours.

Form of

Packaging to 21 pill (11 white and 10 pink). One white tablet contains 0.05 mg levonorgestrel and 0.05 mg etinilestradiola, one pink tablet contains 0.125 mg of levonorgestrel and 0.05 mg etinilestradiola.

All products of this group

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