Directory → Hormones and their antagonists → Estrogens, gestagena; Their homologues and antagonists → Dermestril
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Dermestril

See also Estradiol

Roman name

Dermestril

The composition and the form of

1 tarpaulin covering 9, 18 or 36 cm ^ 2 contains seconds 2, 4 or 8 mg, respectively, the rate of release of the active substance-25, 50 or 100 micrograms per day; in a box 8 pcs. in protective bags.

Of drugs

Mode. Associated with estrogenovmi receptors in kletkah-misheniah and fills a gap seconds in the body, prevents the development of osteoporosis, normalizes exchange lipids.

Indications

Physiological or Postoperative menopause (tides, sleep disorders, urogenitalnaya atrophy, mental instability of mood); Postmenopausny osteoporosis (prevention).

Contraindications

Breast cancer, etc. estrogenzawisimae tumours (diagnostirovanne or suspected), endometriosis, vaginal bleeding of unknown etiology; Severe disorders of the kidneys, liver, cardiovascular system; Embolism and tromboflebita (incl. history), pregnancy, child.

Side-Effects

Headache, pain mammary glands, vaginal bleeding, delay sodium and water, swelling, vomiting, flatulence, causes ulcers, erythema and itching at the application.

Precautions

Be wary appointed in heart failure, kidney dysfunction and liver, severe hypertension, epilepsy, bronchial asthma, diabetes, color, the elderly and gipogonadizme. The regular monitoring of the performance of the endocrine system and gynaecological examinations. Therapy should be stopped immediately when the migraines, frequent headaches and types of disorders.

Dosing and Administration

Nakozhno becloud clean, dry and defatted station intaktna skin on the thigh, the lower back or abdomen (seats chereduyut applications). Treatment starts with a fine patch Dermestril 50. Hanna changed twice a week (along with the days of the week : for example, Monday and Thursday); In the event of otkleivanii patch is replaced with a new one. The maximum daily dose is 100 micrograms. The drug used repeatedly during the three weeks (six applications), followed by one week apart. If hysterectomies shall continuously.

Storage conditions

TTPS : List B. In safe dry place so that the temperature does not exceed 25 ° C

Shelf life

TTPS : 2 grams.

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