Diethylstilbestrol

Chemical name

(E)-4,4'-(1,2-Диэтил-1,2-этен��иил)бис[фенол]

Gross

C18-H20-O2

Characteristics

The white crystalline powder, soluble in alcohol, ether, fatty oils, poorly soluble in water.

Of drugs

Drugs, the mode. It proliferatiou endometrium, which stimulates the uterus and female secondary sexual characters, participates in the formation and maintenance of the strength of bone setting balance between osteoblastami and osteoclastami. Assists гипохолестеринемичес кий effect, reducing the cholesterol / cures by increasing content in the blood alfa-lipoproteidov.

Indications

Cancer prostate cancer, palliative care neoperabelland, complicated cancer, breast cancer (including women).

Contraindications

Diagnosed or suspected tumours of the mammary glands, sexual and other bodies, the propensity to bleeding, tromboflebita, embolic complications (including in history), mastopatia.

Side-Effects

Increased risk of cancer, uterine bleeding, or get amenorea increase and compaction mammary glands, nausea, vomiting, abdominal pain, increased jelchnokamenna disease holetsatical jaundice, headache, dizziness, depression, trochaic, changes in body mass index, oedema, sexual violations, allergic skin rashes.

Dosing and Administration

When prostate cancer cancer : initial dose 1-3 (or more) mg / day supporting dose of 1 mg / sut. When breast cancer appoint 15 mg / sut. The highest daily intake is 60 mg.

Directory → Hormones and their antagonists → Estrogens, gestagena; Their homologues and antagonists → Diethylstilbestrol