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Klimonorm

See also Exemestane

Roman name

Klimonorm

Pharmacokinetics

Valert seconds and levonorgestrel quickly and well imbibed from the digestive tract. Estradiol rapidly metabolised education High 17-beta-estradiola estrona and to be subjected to further metabolic transformations. Seconds valert presented as a metabolites in the urine (90%) and jelchew, levonorgestrel as a kongugatov from urine and jelchew.

Indications

Substitution hormone therapy in pre - and postmenopause, incl. after surgical removal of ovaries; climacteric syndrome (mental and vegetative symptoms) in the period and postmenopause; atrophic skin and mucous membranes (including reproductive organs) in postmenopause, signs of the bladder and mocheispuskatelland channel urinary stress situation (with atrophy sfinkterov bladder); postmenopauznogo preventing osteoporosis.

Pregnancy and lactation

Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.

Contraindications

Гиперчувствительност ь components products, heavy human functions and liver tumors (including in history), congenital malformations lipid exchange embolic processes (including in history), myocardial infarction, acute violation of cerebral circulation, gormonozawisimae tumors uterus, ovaries and mammary glands or suspicion on them, endometriosis and pathological bleeding diseases, diabetes mellitus (severe), angiopatia diabetic; idiopathic jaundice, itching, herpes, progressive otoscleros during the previous pregnancy, pregnancy, breast-feeding.

Patient interaction

Activity reduce PP, triggering biotransformatia steroid hormones : barbiturates nenarcoticeskie analgesics (fenilbutazon), antibiotics (rifampicin, ampicillin, tetracycline, griseofulvin) противоэпилептически е means (carbmazepin, phenytoin).

Overdosing

The increasing incidence described side effects.

Precautions

We use as a method of contraception. Prior to the start of the need to control hospital and Pap-mazok, a survey of the mammary glands and the liver, monitoring AD cholesterol levels in the blood, urine. The caution should be used in people with diabetes, accompanied by changes in pressure and hypertension, varicose veins, flebite, otosclerose, distributed EMG, porfirii, sickle-cell anaemia. The decline in the use of excessive alcohol. The deadline for the preparation migrenepodobnykh frequent headaches, severe violations of sight, hearing and other symptoms of sensory dysfunction, acute trombose, thromboembolitic violations standstill bile, jelthe constant itching feeling, in case of liver tumors, a significant increase in AD frequent seizures, prolonged treatment beds for six weeks prior to surgery. The patients with diabetes may change the mode gipoglikemicakih funds.

Dosing and Administration

The inside is not liquid, after food (preferably the evening), and 1 tablet a day for 21 days beginning with Bean marked number one, and follow the direction of the arrow : first for nine days are yellow beans, the 12-coated brown. After the seven-day break beginning reception in the following package (whether over or continuing haemorrhage). Between premenopauza reception beginning at the 4th day cycle, and menopause, at any time. The duration of the case. In order to prevent osteoporosis therapy is recommended that at least 8 to 10 years or more.

Storage conditions

- List B. In the dark spot.

Shelf life

5 years

The registration

008823

Of drugs

The remedy for the prevention and treatment of menopausal disorders and menstrual cycle.

Indications for use

Climacteric complaints and violations cycle urogenitalnaya dystrophy (reverse development of genital organs), menopause (menopause phase, coming after the last менструально-подобно��о bleeding), atrophy (dryness, thinning), the skin and mucous membranes prevention of osteoporosis (eating disorders of bone tissue, with the increase in the bone associated with changing hormone background) in postmenopause.

Side-Effects

In the first few months of treatment can occur sporadically dizziness, headache, depression (are men), the appetite, a weight soreness mammary glands, changing libido (sexual desire). In a long-term drug, in some cases, there may be a development in the skin brown patches; Time deterioration contact lenses.

Form of

Bonbons in a package of 21 pieces (9 yellow, and cyan 12 colors). 1 jar yellow contains 2 mg seconds valerate, 1 jar cyan color contains 2 mg seconds valerate and 0.15 mg levonorgestrel gestagen.

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