Medroksiprogesteron acetate

Of drugs

The preparation has progestinovoe (such action female sex hormone progesterone), the deprived and androgenna (such action male sex hormones) and estrogenna (such action female sexual hormones-estrogen) activity. In high doses has protivoopujolevoe up at гормонечувствительны х novobrazovaniah malignant. Provides pirogennoe (increase body temperature), the action in high doses has korticosteroidna (such action cortex hormones napochechnikov) activity.

Storage conditions

subst. : In the dark place at a temperature of no higher than 25 ° C

Shelf life

subst. : 5 years

Indications for use

Gormonalnozawisimae forms retidivirutego (repeated) breast cancer from jenshin in menopause (second phase menopause) as a palliative (directed not at the treatment of the disease, and to alleviate the condition of the patient) care; Recurrent and / or metstaticski (accompanied by the appearance of new tumors in other organs and tissues, evolved as a result of the transfer of cancer cells from the blood or lymph from the primary tumors) cancer endometrium (the inner lining of uterus), as an additional and / or palliative care; recurrent and / or metstaticski kidney cancer as an additional and / or palliative care.

Dosing and Administration

The drug use inside or intramuscularly.

Side-Effects

Allergic reactions in the form of Urticaria, rashes, in a few cases -anaphylactoidnykh reactions (allergic reactions immediate type). Embolism (Haaretz receptacle sgustkom blood), throm (inflammation of the walls of veins with their zakuporka); Nervousness, insomnia, weakness, depression (are men), dizziness, headache; Nausea. Changes in the nature of the emissions from the genital tract, the sensitivity of the mammary glands and galactorea (molokoistechenie outside breastfeeding). Pyrogenic response (increased body temperature). In the long admission high doses of the drug may develop syndromic Itsenko-kushinga (obesity and the resulting decline in sexual function, increased bone fractures as a result of the strengthened адренокортикотропног о pituitary hormone).

Contraindications

Hypersensitivity to medroksiprogesteronu or other product components. Pregnancy.

Directory → Hormones and their antagonists → Estrogens, gestagena; Their homologues and antagonists → Medroksiprogesteron acetate