Directory → Hormones and their antagonists → Estrogens, gestagena; Their homologues and antagonists → Novinet
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NovinetSee also ExemestaneRoman nameNovynettePharmacokineticsBoth components quickly and almost completely imbibed from the digestive tract. Estrogens are presistemnomu metabolizmu and compared it with sulphuric and glukuronova acids - enterogepaticescoy circulation. Estrogens presented with the urine (40%) and faeces (60%). T_1/2-26 p.m. Dezogestrel biotransformiroetsa in the liver with the formation of the active-metabolita 3-ketodezogestrela. T_1/2-38 p.m.IndicationsOral contraception.Pregnancy and lactationContraindicated in pregnancy. Is not recommended during breast-feeding because may decrease for milk.ContraindicationsHypersensitivity; Hypertension moderate or severe degrees; Giperlipidemia (family forms); Embolic arterial diseases, including in the disease (myocardial infarction, zerebro-vasculiarnae illness); of a risk of arterial or venous thromboembolism; venous tromboembolia personal or family history; angiopatia diabetic; Whether or in the history of severe liver disease, holetsaticescuu jeltukhu, hepatitis, jeltukhu during pregnancy, depression 12:00-Johnson and fell, swollen liver, porfiriu reception drugs containing steroids; hepatitis (up to the restoration of laboratory parameters and within 3 months after their return); jelchnokamennaya disease; estrogen-zawisimae tumors (including suspicion on them), genital bleeding unknown etiology; systemic lupus red (incl. history); strong itch, genital herpes, otoscleros or otosclerosis deterioration during a previous pregnancy or taking steroids; pregnancy (including suspected it).Patient interactionIn joint application spazmoliticaskie means barbiturates, antibiotics (tetracycline, ampicillin, rifampicin), griseofulvin, laxatives means active complexes some medicinal plants, including John, changing the nature of menstrual reaction or less efficient.PrecautionsIf the tablets reception has been more than 12 hours, the reliability of contraception in this cycle is not guaranteed. In one passage table. at the first or second week cycle should take two table. in the next day, and then regularly. The two leading table row at the first or second week of cycle-2 table. in the next two days to continue, regular admission using additional methods of contraception by the end of the cycle; to release tablets in the third week cycle-more room out Pererav.s special care when using heart disease neishemicescoy etiology, hypertension, diabetes, violations of the kidneys, epilepsy, horee Sidengama, bronchial Astme.sleduet note that oral contraceptives lower tolerance to carbohydrates and increase the need for insulin or oral protivodiabeticakih Sredstwah.vo is receiving a medical checks at least every six months. After carry viral hepatitis can, no earlier than six months (with the normalization of liver functions). If vomiting or diarrhoea, there is a need for further use of a mechanical method of contraception. At the reception, should stop smoking (increasing frequency tromboamboliy various sites, especially for women over 35 years of age). Admission to the three months before the planned pregnancy, four weeks before the operation and long range (eg, after injuries), and immediately when or reinforce migrenepodobna or unusually severe headache, the dramatic deterioration of view, the suspected coronary heart or brain, a sharp rise in AD jelthe Hepatitis or without jaundice, generalizovannom ulcers, or you frequent seizures.Dosing and AdministrationInside (if possible at the same time of day), for the prevention of pregnancy-1 table. a day from 1-5 days menstruation within 21 days, then break 7 days (менструальноподобно�� bleeding), then pills from the following packages (even if the bleeding has not stopped); after childbirth-nekormashchim women 21 days; post-abortion on the one day after the operation.Storage conditionsList B. The temperature 15-30 ° CShelf life3 yearsThe registration014994/01-2003The drug formsDvoyakovpuklae pills pale yellow, forms a disk labeled <R9> on the same side, <RG> on the other side. |
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