Directory Hormones and their antagonists Estrogens, gestagena; Their homologues and antagonists Pauzogest
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Pauzogest

See also Exemestane

Roman name

Pausogest #

The composition and the form of

1 tablet, film coated liner seconds contains 2 mg and noretisteron acetate 1 mg; in a contour acheikova packing 28 pcs. , in a cardboard unit 1, or 3 packaging.

Of drugs

Estrogen-gestagennoe. Whereas women's lack of sexual hormones, eliminates wegeto-sosudistye, psiho-emozionale and other changing estrogenzawisimae symptoms during postmenopauza obstacle to the development of processes giperplasticeskih endometrium, prevents reduction of bone mass and osteoporosis.

Pharmacokinetics

Active substances imbibed from the stomach, metabolised in the liver are mainly urine, mostly in the form of metabolites, and faeces.

Indications

Substitution hormonal therapy in post-menopausal stages; Postmenopauznogo preventing osteoporosis.

Pregnancy and lactation

Contraindicated.

Contraindications

Hypersensitivity, pregnancy or suspected it, cancer breast (including suspicion upon him or that the disease), estrogenzawisimaya tumor or suspected it, liver disease or a history of liver disease, thrombosis of deep veins of lower limbs, embolic disease, cerebrovascular violations, including history, abnormal vaginal bleeding of unknown etiology, haemoglobinopathies, porphyria.

Side-Effects

Menstrualnopodobne bleeding (especially in the early months of therapy), bloating mammary glands, headache, nausea, peripheral edema, rarely impaired vision, skin reactions to long-term therapy, a disease mammary glands, embolic state.

Patient interaction

Effect reduce funds for narcosis, opioid analgesics, anxiolitiki, some gipotenzivee means induktora liver enzymes, ethanol.

Overdosing

Symptoms : high doses, nausea, vomiting, breeding Krovotechenie.lechenie : symptomatic.

Precautions

With great care use in patients with epilepsy, migraine, diabetes, asthma and heart disease. Four to six weeks prior to surgical interventions should stop treatment. Prior to the start of treatment to rule out a malignant neoplasms. Therapy should be immediately interrupted by the emergence of the following side effects : thrombosis deep vein, including embolic complications, the development of jaundice, a migrenepodobna headache, the sudden deterioration / impaired vision expressed by the AD. With long-term therapy at least once a year a preventive examination. When combined with therapy antigipertenzivna a regular monitoring AD. If you are a gipoglikemicakih funds may need to be adjusted their doses.

Dosing and Administration

Inside, 1 tab. once a day for 28 days (without interruption). Therapy beginning not earlier than one year after the menopause.

Storage conditions

tabl.p.p.o. : The temperature 15-30 ° C

Shelf life

tabl.p.p.o. : 3 and

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