Directory Hormones and their antagonists Estrogens, gestagena; Their homologues and antagonists Sinestrol
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Sinestrol

See also Hexestrol

Roman name

Synoestrolum

The composition and the form of

Sinestrol 1, or 20 g, auxiliary substances (or olive oil persikovoe) - 1L.

Of drugs

Sinestrol is a synthetic compound-stilbene derivative. The chemical structure differs from steroid hormones oestrogen (female sex hormone), but the biological and curative properties close to them. Estrogens-female sex hormones produced by the ovaries and cerebral layer napochechnikov cause of female genitalia, secondary sexual characteristics, as well as contribute to proliferation (spread) endometrium cells (internal layer uterus).

Storage conditions

r-r d / in.masl. : List B. In the dark spot

Shelf life

r-r d / in.masl. : 5 years

Indications for use

Women basically the same as testimony to the application follikulina. Sometimes appointed to atrophy (increase), and cancer prostate cancer in men.

Dosing and Administration

Misleading injection under the skin and inside out; Injection under the skin in oil solutions, inside-tablets. Entering into sinestrol rapidly absorbed; Not destroyed in the gastrointestinal tract.

Side-Effects

Sinestrol usually well tolerated. In some cases, have nausea, vomiting, dizziness. When taken large doses may be toxic damage to the liver, excessive proliferation endometrium (increased and the masses of the inner lining of uterus), and bleeding in women expressed feminization of men (decrease sexual function induced mammary glands, indications nipples, the reduction of pain, etc.).

Contraindications

Sinestrol and its analogues protivopokazana of pregnancy, liver and kidney diseases.

All products of this group

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