Directory Hormones and their antagonists Hormones hypothalamus, pituitary, gonadotropin and their antagonists Adiuretin tilt
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Adiuretin tilt

See also Desmopressin

Roman name

Adiuretin # SD

The composition and the form of

1 USD 1 ml solution for injection contains desmopressina acetate 4 g; in a box st.1 5 ml for backfilling nose-0.1 mg (1 drop-5 g); flakonah-kapelnytsah in 5 ml, in the box one bottle.

Of drugs

Вазопрессиноподобное . And antidiureticski action activates factor VIII closings and increases plazmaticski plazmina activator.

Farmakodinamika

In nesharnom diabetes increases reasorbqiyu water from the distal renal channel while increasing the relative density osmoticescuu urine. This helps to reduce the frequency and mocheispuskani address the needs of black liquid.

Indications

Drops : nesharnyi diabetes, nighttime urinary; In the study of the ability Concentrate Pocek.rastvor injection : nesharnyi diabetes (diagnosis and treatment), the acute poliuria after operations gipofize, hemophilia, a disease Villebranda.

Contraindications

Hypersensitivity; State, accompanied by low relative density osmoticescoy blood plasma, incl. psychogenic and polideepcia familiar; delay liquids of different etiology, including with chronic heart failure; anuria.

Side-Effects

Nausea, vomiting, spasticskie pains in the abdomen, headache, difficulty urinating, increased sweating, nasal irritation nasal cavity.

Precautions

Concentrate Study of kidney should perform child qualified. Children under 1 year of concentration test with the board Adiuretinom in exceptional cases. The high doses of the children under one year could lead to the development convulsing and other neurological and psychiatric symptoms. In the case of the test in children under 1 year during the time of urine collection should be deleted reception liquid.

Dosing and Administration

Intranasal in nesharnom diabetes for 1-3 drops two or three times a day. When night nederjanii urine, 2-10 drops overnight. In / in and / m in nesharnom diabetes-1 ml (1 USD) for 8 h, higher doses should be in / in slowly, in the form of drip infusions. Injections are also used when it is impossible intranazalnoe use, or require a more precise study Dozirovca.pri Concentrate ability kidney : recommended dose 3 drops (about 15 µ g), for children over the age of 1 year, 2-3 drops (about 10-15 g). Immediately after the patient must : emptying the bladder and at the time of the test, as well as 6700, after the (first 8 h) to limit the flow of liquid. Over the next four hours after the use of the drug every hour collect urine samples of the patient to determine osmolarnosti. If, as a result of a test drop Concentrate ability kidney-test shall be Povtoriti.pri of acute central poliurii : route to 2 drops. The actions to be expected after 30 min. During one hour of the balance of fluids in the form of infusions and diureza should return to normal. If, in the course of one hour is not good balance, it is recommended to move to the introduction of sex (often in / w).

Storage conditions

drops open. : List B. In cool the dark place at a temperature of 15 ° Cr-r d / in. : In cool the dark place at a temperature of 15 ° C

Shelf life

drops open. : 2 gu.r-r d / in. : 2 grams.

Indications for use

Assign nesharnom with diabetes (disease caused by the absence or reduction secreta antidiuretic / less mocheotdelenie / hormone), Shields (Night nederjanii urine).

Form of

0.01% solution (1 ml = 0.1 mg) tablets in 5 ml of пробками-капельницам��.

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