Directory Hormones and their antagonists Hormones hypothalamus, pituitary, gonadotropin and their antagonists Adiuretin
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Adiuretin

See also Desmopressin

Roman name

Adiuretin #

The composition and the form of

1 ml drops for the nose desmopressina acetate 0.1 mg (1 drop-5 g); flakonah-kapelnytsah in 5 ml, in the box one bottle.

Of drugs

Вазопрессиноподобное . And antidiureticski action activates factor VIII closings and increases plazmaticski plazmina activator.

Farmakodinamika

In nesharnom diabetes increases reabsorbqiyu water from the distal renal channel while increasing the relative density osmoticescuu urine. This helps to reduce the frequency and mocheispuskani reduce fluid intake.

Indications

Nesharnyi diabetes, nighttime urinary; In the study Concentrate to the kidneys.

Contraindications

Hypersensitivity; State, accompanied by low relative density osmoticescoy blood plasma, incl. psychogenic and polideepcia familiar; delay liquids of different etiology, including with chronic heart failure; anuria.

Side-Effects

Nausea, pain in the abdomen, headache, cough, active bleeding.

Precautions

Concentrate Study of kidney should perform child qualified. Children under 1 year of concentration test with Adiuretinom in exceptional cases. The high doses of the children under one year could lead to the development of convulsing caused by irritation nervous system. In the case of the test in children under 1 year during the time of urine collection should be deleted reception liquid.

Dosing and Administration

Intranasal in nesharnom diabetes : the 1-3 drops 2-3 times a night Sutki.pri nederjanii urine : 2-10 drops overnight (dose chosen individually). The study Concentrate ability kidney : recommended dose 3 drops (about 15 µ g), for children over the age of 1 year, 2-3 drops (about 10-15 g). Сразу после введения пациенту необходимо опорожнить мочевой пузырь и на время проведения теста и в течение 4 ч после его окончания (всего 8 ч) ограничить поступление жидкости. Over the next four hours after the use of the drug every hour collect urine samples patient to determine osmollnosti. If, as a result of a test drop Concentrate ability kidney-test shall be Povtoriti.pri of acute central poliurii : route to 2 drops. The actions to be expected after 30 min. During the one hour a balance between the flow of the liquid in the form of infusions and diurezom should return to normal. If, in the course of one hour is not good balance, it is recommended to move to the introduction of sex (often in / w).

Storage conditions

drops open. : List B. In the dark place at a temperature of 2-8 ° C. Protect from freezing.

Shelf life

drops open. : 2 grams.

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