Directory Hormones and their antagonists Hormones hypothalamus, pituitary, gonadotropin and their antagonists Biosoma
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Biosoma

See also Somatropin

Roman name

Biosoma #

The composition and the form of

1 bottle with liofilizirovannam powders for the preparation of injection solution contains recombinant growth hormone rights 1.4 mg (Biosoma 4 IU), or 2.8 mg (Biosoma 8 IU); per bundle one with a bottle liofilizirovannam powder for injection (4 or 8 IU) complete with one vial solvent (2.2 ml of 0.9% benzyl alcohol), two syringes and two needles.

Of drugs

Stimulating growth. Faster increase in tubular bones, to the synthesis of protein.

Indications

Poor growth in children with gipopithuitarizme (deficiency of growth hormone); Turner syndrome.

Contraindications

Hypersensitivity, the closure epifizov, cancer.

Side-Effects

Hypothyreosis thyroid gland.

Patient interaction

The antagonism with tirokshinom. Glukokortikoida reduce effectiveness.

Overdosing

Early Symptoms gipoglikemii later-io.

Precautions

Treatment out under strict supervision vracha-endokrinologa. If there are any injuries in the head, as well as when a growth hormone deficiency due to organic lesion brain requires special study. During treatment to monitor periodically the thyroid gland and, as necessary, appoint tireoidnye hormones. For patients with a concomitant deficit ACTG very carefully picked dose substitution therapy. In diabetes sometimes increasing the dose of insulin. The contents of dissolving hair only in the attached solvent; Use syringes included in the package; Not to use surplus prepared solution stored more than 6 days.

Dosing and Administration

P / to the evening. Doses picked individually. In stunting - 0.6-0.7 IU / kg or 18 IU / m ^ 2 body surface per week (divided into 6-7 injection). In long-term care, children older (at puberty), and Turner's syndrome, and 1 IU / kg / week or 30 IU / m ^ 2 weeks (divided into 6-7 injection). Treatment begin as soon at an earlier age and continue until the closing of growth zones bones, or to achieve the desired growth.

Storage conditions

por.liof.d / in. : List B. In the dark place at a temperature of 2-8 ° C. Cooked Solution 6 days at a temperature of 2-8 ° C.

Shelf life

por.liof.d / in. : 2 grams.

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