Directory → Hormones and their antagonists → Hormones hypothalamus, pituitary, gonadotropin and their antagonists → Menopur
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MenopurSee also MenotropinsRoman nameMenopurThe composition and the form of1 bottle with liofilizirovannam powders for the preparation of injection solution contains menotropina (human menopauznogo gonadotropina) 75 IU, together with the solvent in the USD 1 ml; in a carton 5 or 10 kits.Of drugsGonadotroponoe. Contains opened LG and in the ratio of 1:1. Women stimulates growth and maturation in follikulov aicnikah and proliferatiou endometrium increases estrogen levels; Men stimulates spermatogenez.IndicationsWomen : infertility due гипоталамо-гипофизар��ыми violations of assisted reproductive technologies for the Zachatia.u men : azoospermia and oligoastenspermia due to a primary or secondary gipogonadotroponam gipogonadizmom (in combination with AZT human horioniceski gonadotropina - Chg).ContraindicationsГиперчувствительност ь. For women : persistirutee increase ovaries, or an ovarian cyst is not due syndrome polikistozhnykh ovaries, abnormalities of the reproductive organs, uterus mioma incompatible with pregnancy; Vaginal bleeding unclear etiology, cancer of the ovaries, uterus or mammary gland; Primary ovarian failure; Pregnancy; Feeding Grudew.dl men : prostate cancer cancer or other androgenozawisimae tumors.Side-EffectsFor part of the intestine : nausea, Rvota.so the urogenital system : moderate (neoslojnennoe) increase in ovarian cancers and education ovarian cyst, giperstimulyatsii syndrome ovaries (expressed pain at the bottom of the abdomen, nausea, vomiting, increased body mass index, gipovolemia increase in erythrocyte plasma associated with a decrease in the volume of plasma electrolytes imbalance, liver, gemoperitonium, gidrotoraks, tromboamboliceski синдром).Аллергически е reactions : the body temperature, skin Sapi.prochie : education antibodies, in the injection-pain, redness, swelling or itching.Specific guidanceDose to stimulate growth of the dominant follicle prepared individually and depend on the reaction of men. Optimal dose and duration of treatment established on the basis of ultrasound ovarian cancer, the level of estrogen in the blood and clinical observation. About follicle maturation tried to increase the level of estrogen in the blood.Dosing and AdministrationV / m or m / GMT Infertility among women due гипоталамо-гипофизар��ыми violations : usually start with doses of 75-150 IU (1-2 mg) a day, in the absence of a reaction ovaries dose gradually increase to the increased estrogen in the blood or growth follikulov and remain until preovulatornogo estrogen level. For the induction of ovulation in 1-2 days after the last injection once impose ME.U 5,000 men, with a view to stimulating spermatogeneza pre-enter 1,000-3,000 IU Chg three times a week; After normalization of the level of testosterone in the blood type of Menopur 75-150 IU (1-2 mg) three times a week for several months.Storage conditionspor.liof.d / in. : List B. In the dark place at a temperature of no higher than 25 ° CShelf lifepor.liof.d / in. : 2 grams. |
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