Directory Hormones and their antagonists Hormones hypothalamus, pituitary, gonadotropin and their antagonists Metrodin vc
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Metrodin vc

See also Urofollitropin

Roman name

Metrodin HP #

The composition and the form of

1 USD dry material for the preparation of the injection urofollitropina high degree of purification 75, or 150 IU together with the solvent in the USD 1 ml; in the package 1 and 10 pcs.

Characteristics

Metrodin frequency is determined by the technology, which allows a drug to the degree of treatment more than 95%.

Of drugs

Фолликулостимулирующ ее. It stimulates the growth and maturation follikulov increases the level of estrogen, activates proliferatiou endometrium.

Indications

Infertility (incl. unknown etiology) : stimulation of the dominant follicle in patients violation гипоталамо-гипофизар��ых relationship (including with such syndrome polikistozhnykh ovaries), the growth stimulation of multiple follikulov in support of reproduction.

Pregnancy and lactation

Contraindicated.

Contraindications

Гиперчувствительност ь menotropinam to; persistirutee increase ovaries, or an ovarian cyst (not from polikistoza syndrome); abnormalities of the reproductive organs (incompatible with pregnancy), mioma cancer, gynaecological bleeding unknown etiology, cancer of the ovaries, uterus and mammary gland, the primary ovarian failure.

Side-Effects

There may be 3-5% of the cases : Diarrhoeal disorders, pain in epigastralna area and the lower abdomen divisions, flatulence, fever, arthralgia, pain in the mammary glands and in the injection, a modest increase and education ovarian cyst. Syndrome giperstimulyatsii cancer : early warning signs, expressed pain at the bottom of the abdomen, nausea, vomiting, increased body weight, late (could lead to fatal) - gipovolemia, an imbalance of electrolytes, liver, gemoperitoneum, plevralny vpot, gidrotoraks, tromboembolia.

Patient interaction

Klomifen-zitrat can increase response hair. Using Gnrg agonists, as a general rule, an increase in dose metrodin. It should not be mixed with other drugs in a single sprite.

Dosing and Administration

P / to and / m (solution prepared immediately before use). At 75-150 IU in the first seven days of the cycle, or every other day for 225-375 IU in a week. If ovulation, and the lack of pregnancy rate can be repeated at least twice (2-cycle).

Storage conditions

por.liof.d / in. : List B. The temperature is not above 25 ° C

Shelf life

por.liof.d / in. : 3 and

All products of this group

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