Directory → Hormones and their antagonists → Hormones hypothalamus, pituitary, gonadotropin and their antagonists → Metrodin vc
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Metrodin vcSee also UrofollitropinRoman nameMetrodin HP #The composition and the form of1 USD dry material for the preparation of the injection urofollitropina high degree of purification 75, or 150 IU together with the solvent in the USD 1 ml; in the package 1 and 10 pcs.CharacteristicsMetrodin frequency is determined by the technology, which allows a drug to the degree of treatment more than 95%.Of drugsФолликулостимулирующ ее. It stimulates the growth and maturation follikulov increases the level of estrogen, activates proliferatiou endometrium.IndicationsInfertility (incl. unknown etiology) : stimulation of the dominant follicle in patients violation гипоталамо-гипофизар��ых relationship (including with such syndrome polikistozhnykh ovaries), the growth stimulation of multiple follikulov in support of reproduction.Pregnancy and lactationContraindicated.ContraindicationsГиперчувствительност ь menotropinam to; persistirutee increase ovaries, or an ovarian cyst (not from polikistoza syndrome); abnormalities of the reproductive organs (incompatible with pregnancy), mioma cancer, gynaecological bleeding unknown etiology, cancer of the ovaries, uterus and mammary gland, the primary ovarian failure.Side-EffectsThere may be 3-5% of the cases : Diarrhoeal disorders, pain in epigastralna area and the lower abdomen divisions, flatulence, fever, arthralgia, pain in the mammary glands and in the injection, a modest increase and education ovarian cyst. Syndrome giperstimulyatsii cancer : early warning signs, expressed pain at the bottom of the abdomen, nausea, vomiting, increased body weight, late (could lead to fatal) - gipovolemia, an imbalance of electrolytes, liver, gemoperitoneum, plevralny vpot, gidrotoraks, tromboembolia.Patient interactionKlomifen-zitrat can increase response hair. Using Gnrg agonists, as a general rule, an increase in dose metrodin. It should not be mixed with other drugs in a single sprite.Dosing and AdministrationP / to and / m (solution prepared immediately before use). At 75-150 IU in the first seven days of the cycle, or every other day for 225-375 IU in a week. If ovulation, and the lack of pregnancy rate can be repeated at least twice (2-cycle).Storage conditionspor.liof.d / in. : List B. The temperature is not above 25 ° CShelf lifepor.liof.d / in. : 3 and |
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