Oktreotida solution

Roman name

Solutio Octreotidi

The composition and the form of

1 ml oktreotida contains 100 micrograms; USD in 1 ml (complete with ampulnam knife), in a Box 5 pcs.

Of drugs

Соматостатиноподобно е. Ingibiruet increased secretion of growth hormone, as well as peptides and serotonin produced in гастроэнтеропанкреат ической endocrine system. Suppress the gastric juice, and gastrina pepsina; Viszeralny reduces blood; Suppresses the secretion of the pancreas, gall bladder and intestines. Provides zitoproteguoe effect on the cells parenhima pancreas, liver and stomach.

Pharmacokinetics

After p / to a fast and fully absorbed. C_max achieved in 30 min. Linking protein-65% of total Cl-160 ml / min, T_1/2-100 min. After the on / in the development of injections carried out in two phases with T_1/2 10, and 90 min.

Indications

Acute pancreatitis; Prevention and treatment of postoperative complications after surgery for pancreatic cancer (for the decrease in the development of pancreatic fistula, abscesses, septicaemia, acute pancreatitis post); Gastroduodenale haemorrhage (ulcerative and varikozno expanded veins oesophagus, including in patients with cirrhosis of the liver).

Contraindications

Гиперчувствительност ь (including components preparation).

Side-Effects

For part of the intestine : in rare cases, anorexia, nausea, vomiting, venous and pain in the abdomen, bloating, voltage abdominal wall, diarrhoea, steatorea, the acute intestinal Neprokhodimosti.so the metabolism : the tolerance glukoze to, in rare cases, persistirutaya hyper or Gipoglikemia.mestnye reactions : pain, hyperemia, itching sensation and / or pain, erythema, swelling at the site of (being within 15 minutes).

Patient interaction

Wrinkles removals zimetidina and reduces - cyclosporine.

Overdosing

Symptoms : aetiology, tides blood to a person, diarrhea, nausea, a feeling of emptiness and / or pain in Jeludke.lechenie : symptomatic.

Dosing and Administration

P / to, in stark pankreatite by 100-300 µ g 3-4 times a day for three to five days, preventing complications after operations on the pancreas-100 µ g for 1 h to Chapter, and then after the operation, 100 µ g three times a day for up to 7 days. When stopping bleeding in the digestive tract-50 µ g / h in the form of infusions over five days.

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