Directory Hormones and their antagonists Hormones hypothalamus, pituitary, gonadotropin and their antagonists Pergonal
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Pergonal

See also Menotropins

Roman name

Pergonal #

The composition and the form of

1 USD with liofilizirovannam powders for the preparation of injection solution contains menotropina (human gonadotropin Foundation containing opened and LG in the ratio 1:1) 75, and 150 IU; together with the solvent in the USD 1 ml (solution of sodium chloride for injection), in one package, or 10 kits.

Of drugs

Pergonal belongs to the group menotropinov (prepatov menopauznogo human gonadotropina - hormones front of pituitary, proactive sexual glands). Contains фолликулостимулирующ ий (enabling the ripening eggs) and luteiniziruuchi (education causes yellow body cancer) hormones in the ratio of 1:1, the ekstragirovaniem (profit) from the urine of women in menopause (second phase menopause).

Indications

For women, infertility : growth stimulation of hair, and the violation гипоталамо-гипофизар��ых relationship or gipogonadotroponam gipogonadizmom (with anovulatoriani violations), the growth stimulation of multiple follikulov. Men-primary and secondary gipogonadotropony gipogonadizm, azoospermia, oligoastenspermia.

Contraindications

Persistirutee (permanent) increase in ovarian cancer or a cancer cyst is not due to the syndrome polikistozhnykh ovaries; Abnormalities of the reproductive organs or mioma (Good tumour from developing muscle) uterus incompatible with pregnancy; Gynaecological bleeding unknown etiology (cause); Cancer of the ovaries, uterus or mammary gland; Primary ovarian failure; cancer prostate cancer or any other androgenzawisimae tumors (tumors that are dependent on the level of male sex hormones in the blood) in men; pregnancy; breast-feeding; in the history (history) on the high degree of sensitivity to menotropinam (particularly pergonal drugs, or metrodin pergogrin containing luteiniziruty and / or �олликулостимулирующ��й hormones).

Side-Effects

The pain at the injection, gastrointestinal disorders, flatulence (gas accumulation in the gut), the pain in epigastralna area (the abdomen, located directly beneath mud arches rib and the sternum), or at the bottom of the abdomen; Moderate (neoslojnennoe) increase in ovarian cancers and education ovarian cyst (a process characterized by the formation of cavities exported); giperstimulyatsii syndrome, the ovaries expressed pain at the bottom of the abdomen, nausea, vomiting, increased body mass index (early warning signs); gipovolemia (decrease volume of circulating blood), gemokoncentration (decrease in the number of the liquid part of blood kept in uniform content elements), an imbalance of electrolytes (the ion balance), the liver (fluid accumulation in the abdominal cavity), gemoperitonium (accumulation of blood in the abdominal peritoneum) gidrotoraks (fluid accumulation in the chest cavity), tromboamboliceski syndrome (Haaretz sgustkom blood). Rush (a sharp increase in body temperature), arthralgia (kneecap pain), pain in the milk glands; Ginekomastia men (increase mammary glands of men).

Patient interaction

Incompatible in one sprite with other drugs.

Precautions

Prior to the start of treatment should be therapy hypothyroidism, giperprolaktinemii, pituitary tumors or hypothalamus.

Dosing and Administration

Pergonal impose injection. Solution for injection preparation immediately preceding the imposition of using solvent attached. In 1 ml solvent can be existed until 5 vials containing active substance. Cooked injection drug use immediately.

Storage conditions

por.liof.d / in. : List B. The temperature is not above 25 ° C

Shelf life

por.liof.d / in. : 3 and

Indications for use

Women growth stimulation follikulov with barrenness due гипоталамо-гипофизар��ыми violations with a view to stimulating growth of the dominant follicle; in the assisted reproductive technologies (in vitro fertilization) for the conception (growth stimulation multiple follikulov). Men stimulation spermatogeneza (education male sex cells), with azoospermy (no sperm in the semen), or oligoastenspermy (reducing volume / Semen /), from the primary or secondary gipogonadizmom (lower education hormones as a result of the breach of the pituitary), in combination with therapy human horioniceski gonadotropinom.

Form of

Dry chemical injection in ampoules containing 75 or ME 150 ME фолликулостимулирующ его and luteiniziruuchego hormone combination with the solvent in the USD 1 ml packages to 1 or 10 pieces.

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