Directory Hormones and their antagonists Hormones hypothalamus, pituitary, gonadotropin and their antagonists Somatulin
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Somatulin

See also Lanreotide

Roman name

Somatuline #

The composition and the form of

1 orange powder (in the form of microspheres pace with the slow-release) for solution for injection contains lanreotida acetate 30 mg; together with the solvent (in ml), and injected two needles, in a cardboard bundle 21.90.

Of drugs

Соматостатиноподобно е. Suppress increased secretion of growth hormone, as well as liberatiou peptides and serotonin produced in гастроэнтеропанкреат ической endocrine system.

Indications

Akromegalia related violations secreting growth hormone after surgery and / or radiotherapy, symptomatic therapy with carcinoid tumors.

Contraindications

Hypersensitivity, pregnancy, lactation.

Side-Effects

Nausea, vomiting, anorexia, spasticskie pains in the abdomen, bloating, diarrhea, and rarely extended to the treatment of asymptomatic, cholelithiasis; In rare cases, the transient blood glucose (does not require insulin treatment); Tranzitornaya moderate pain at the injection, sometimes accompanied by giperemiei.

Specific guidance

The / m injection should be carried out in strict accordance with the regulations. Each injection, after which the sprite to be drug more than instruction shall be recorded.

Precautions

Treatment should be conducted in the specialized agencies. Caution should be appointed patients with diabetes (only continuously monitored blood glucose). Patients who are insulinzawisimam diabetics, insulin dose should be reduced by 25%, and then determined in accordance with the concentration of glucose in the blood. In appointing the akromegalia should continue monitoring of pituitary tumors. In carcinoid tumors should not begin treatment lanreotidom until intestinal obstruction cancer. Before the start of treatment and every six months of therapy should be patient gallbladder. The acute and long steatorei requires additional prescriptions pankreatina. In patients with renal and hepatic insufficiency should be carefully monitored as these bodies and adapt the dosage,

Dosing and Administration

V / m. When treating akromegalia and clinical symptoms kartsinomnah tumors that start with a pilot injection for response assessment (secretia growth hormone, the symptoms associated with the tissue tumour secretia tumors, etc.). If the response to 30 mg once every 14 days, in the event of inadequate performance every 10 days.

Storage conditions

por.liof.d / in. : List B. The temperature of 2-8 ° C. In the refrigerator.

Shelf life

por.liof.d / in. : 17 months

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