Directory → Hormones and their antagonists → Hormones hypothalamus, pituitary, gonadotropin and their antagonists → Tetracosactide
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TetracosactideChemical nameальфа-(1-24)-Кортикотроп ин (and in the form of acetate)GrossC136-H210-N40-O31-SOf drugsThe drugs-glukokortikoidne, минералокортикоидное . Does bark napochechnikov (адренокортикотропно�� Effects). Interfaces with plazmaticakimi receptor, activates adenilatziklazu, education and Zamf Zamf-zawisimah proteinkinaz, Tiofat key enzymes and eukaryotes.IndicationsDiffuse disease connective tissue (rheumatoid arthritis, etc.), allergic diseases (bronchial asthma, angioneuroticeski swelling), Medicine, sexually abstinent (Baby Ulcerative Colitis).ContraindicationsHypersensitivity, acute psychosis, saying disease stomach and duodenal ulcers, heart failure, pregnancy, breast-feeding.Side-EffectsLower resistance to infections, personality disorders, osteoporosis, erosivno-azwenne defeat tract, skin pigmentation.Specific guidanceIt vigorously shaking sealed before use.Patient interactionReduces effect protivodiabeticakih oral drugs increases, cardiac glycosides, modifies - dioretikov. Ketokonazol weakens stimulating effect on the adrenal glands.PrecautionsWith long-term use drugs to be adding a body potassium.Dosing and AdministrationB / m-1 mg a day, the acute cases, and 1 mg every 12 h after the disappearance of critical phenomena, to 1 mg every 1-2 days, followed by dose reduction to 0.5 mg in 2-3 days or 1 mg once a week; Children every 1-7 days in the dose of 0.25 mg (pectoral age), 0.25 mg (younger age) or 0,25-1 mg (school age).See also |
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