Directory → Hormones and their antagonists → Hormones hypothalamus, pituitary, gonadotropin and their antagonists → Humatrop
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HumatropSee also SomatropinRoman nameHumatrope #The composition and the form ofLiofilizirovanny powder for injection preparation solution in vials to 4 IU, together with the solvent in vials of 2 ml or cartridges for the devices Humatropen II on 18 and 36 IU / ml, together with the solvent.CharacteristicsBiosinteticeski rekombinantny growth hormone rights polipeptidnaya chain includes 191 acid balance (in the sequence identical to the human gormonu growth).Of drugsAnabolicescoe, giperglikemicescoe. It stimulates the growth of the skeleton and increases the number and size of muscle cells mobilize fats, delaying sodium, potassium, phosphorus.IndicationsViolation of growth hormone deficiency growth, Turner syndrome.ContraindicationsГиперчувствительност ь (incl. to m-krezolu or glitzerino) closed epifiza, active Cancer process and the anticancer therapy, signs of tumour growth, the severe intracranial trauma.Side-EffectsGiperglikemia, reduced tolerance to glukoze, tranzitornyi otechny syndrome, the symptoms of hypothyroidism.Patient interactionGlukokortikoida weaken effect.Dosing and AdministrationV / m, p / model Dose and spacing of selected individually (up to 0.48 IU / kg per week). The lack of growth hormone, to 0.48 IU / kg per week, with Turner syndrome, 0.8-0.9 IU / kg, which is equivalent to 28 IU / m ^ 2 body surface per week. Weekly dose is divided into 6-7 injections and introduced overnight. For long-term therapy, it was necessary to monitor the concentration in the blood glucose and tireoidnykh hormones.Storage conditionspor.liof.d / in. : List B. The temperature of 2-8 ° C. Cooked solution is stable 21 days at a temperature of 2-8 ° C. Do not freeze.Shelf lifepor.liof.d / in. : 2 grams. |
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