L-tiroksin 100 berlin-hemi

Roman name

L-Thyroxin 100 Berlin

The composition and the form of

Pill-1 tabl.levotiroksin sodium-50 mcg- 100 mcgv blistere 25 pcs. ; In a Box 2 (50 and 100 µ g) or 4 (100 µ g) blisters.

Pharmacokinetics

Absorbed in a thin leg by 80% (to prandial). S_max plasma is approximately six hours after admission. Linking plasma protein-more than 99%. Cl metabolic about 1.2 litres of plasma a day. Destroyed mainly in the liver, brain and muscles.

Indications

Hypothyroidism primary, secondary, congenital and acquired (after the operation, a conservative treatment, as a result of tireoidita or other diseases); Eutireoidnyi goitre (as a stand alone treatment or in combination with Yodomarinom 200); In the treatment of hyperthyroidism tireostaticakimi drugs after eutireoidnyi condition; supressus therapy after surgery on the thyroid gland and treatment of radioactive iodine for the prevention of recurrence of the tumor.

Pregnancy and lactation

During pregnancy treatment should continue. At the same time, tireostaticakimi means to penetrate the placenta and may cause fetal gipofunktia thyroid, a not recommended.

Contraindications

Hyperactive thyroid any origin, acute myocardial infarction, nelechennaya lack napochechnikov crust.

Side-Effects

When properly used under the supervision of the physician side-effects have not been observed. In case of hypersensitivity to the drug could experience allergic reactions.

Patient interaction

Ters effect of insulin and oral protivodiabeticakih means more indirect anticoagulants. Phenytoin, salicilata, dikumarol, furosemide (in high doses), klofibrat more content in the blood. Holestiramin suppresses induction.

Overdosing

Is tireotoxicoza symptoms. The reception beta-adrenoblokatorov, plazmaferez.

Precautions

Be wary appoint elderly patients with ischemic heart disease, heart failure and tachycardia. Particular caution is needed in the treatment of patients with hypertension who suffer epileptic insufficient function napochechnikov crust, in patients with severe gipofunktion thyroid, or if the reduced function is a long time.

Storage conditions

List B. In the dark spot

Shelf life

3 years

The registration

008964

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