Directory → Hormones and their antagonists → Hormones thyroid cancer, a month and antagonists (including antitireoidnye means) → Tireotom
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TireotomSee also Lithium iodideRoman nameThyreotom #The composition and the form of1 tablet contains levotiroksina 40 µ g and liotironina 10 µ g; Patients in the 60 pcs. , in the box one bottle.Of drugsTireoidne. Acts for the lack of production of hormones the thyroid gland (increases the exchange, increases the disintegration of proteins, carbohydrates, fats).PharmacokineticsLiotironin (triyodtironin) is faster than levotiroksin (tiroksin), less contact with the blood protein is transported in the blood mainly in the form of free and faster to cross the cell membrane.FarmakodinamikaIncreases oxygen demand, increased energy processes, stimulates growth and differentiation of tissues, affects the functional state of the nervous and cardiovascular systems, liver, kidneys and other organs, increases glucose intake and its disposal. Liotironin 3-5 times more efficient than levotiroksin. The latent period is liotironina 4-8 hour levotiroksina - 24-48 hoursIndicationsHypothyroidism, eutireoidnyi goitre prevention of relapse weeks (after POE thyroid gland); The overwhelming and substitution therapy to malignant tumors thyroid (especially after the removal of the thyroid gland); Additional therapy in the treatment of hyperthyroidism tireostaticakimi drugs (after eutireoidnyi state).ContraindicationsRay, acute myocardial infarction, stenocardia and myocardial infarction in elderly patients, myocarditis, asthma napochechnikovaya failure.Side-EffectsSymptoms of hyperthyroidism (shaky fingers, tachycardia, increased sweating, insomnia, glukozuria, stenocardia, adults, diarrhea, treatmentoptions, anxiety), a temporary increase in body mass index, alopecia, a violation of the kidneys and the propensity to cramps (children).Patient interactionEffect increase phenytoin, dikumarol, salicilata, furosemide, klofibrat reduces - holestiramin (suppresses induction). Increases of oral anticoagulants, reduces - protivodiabeticakih funds.Dosing and AdministrationInside, erh, squeezed small amounts of liquid. The dispensing individual adults therapy usually start with 1/2-1 table. once a day, increasing the dose at intervals of 2-4 weeks prior to the pro-table 3-6.Storage conditionstable. : List B. In the dark spotShelf lifetable. : 3 andIndications for useHypothyroidism (downgrading of the thyroid gland), eutireoidnyi goitre (pathological increase the thyroid gland which is not accompanied by violations of its functions), prophylaxis and therapy of recidivism (re-development) after POE (disposal) goitre.Form ofAnswers to 0.05 mg in a package of 60 pieces. One tablet contains triyodtironina 0.01 mg, 0.04 tiroksina mg. |
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