Directory → Hormones and their antagonists → Hormones thyroid cancer, a month and antagonists (including antitireoidnye means) → Yodtirox
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YodtiroxSee also Lithium iodideRoman nameJodthyrox #The composition and the form of1 таблетка содержит левотироксина натрия 100 мкг и калия йодида 130,8 мкг (соответствует 100 мкг йода); в пластиковых пеналах по 50 или 100 шт., в картонной пачке 1 пенал.Of drugsCombined preparation containing levotiroksin preparation and inorganic iodine. Iodtirox designed for therapy and prophylaxis eutireoidnyi goitre (abnormal increase in the thyroid gland) in the face of iodine deficiency. The lack of iodine decreases tiroksina synthesis of the thyroid gland, which increases the blood tireotroponogo pituitary hormone to regulate the thyroid gland), followed by the development of hyperplasia (tissue growth), the thyroid gland. Isolated intake of iodine blocking secretion (a) tireotroponogo hormone, which could lead to oppression tiroksina synthesis. Adding levotiroksina compensates tiroksina deficit, and also suppresses excessive synthesis tireotroponogo hormone. In addition, the combined use of levotiroksina and iodine products for the treatment and prevention of relapse (recurring) endemic goitre (diseases of the thyroid gland, with the increase due to low iodine content in the water) to reducing the number of cases of unwanted long reception iodine (such as braking tireoidnykh synthesis of hormones / hormones thyroid / change the sensitivity of the thyroid gland to tireotroponomu gormonu).IndicationsTreatment eutireoidnyi deaths among children, adolescents, adults, including during pregnancy; substitution therapy in gipotireoze, preventing relapse weeks after surgical removal.ContraindicationsIncreased sensitivity to iodine, clinically pronounced Ray (disease characterized by increased function of the thyroid gland), adenomatous goitre (node in the thyroid gland), tumors of the thyroid gland. The agent shall carefully cardiac patients, including both hypertension (raising blood pressure), stenocardiu, myocardial infarction, human heartbeat rhythm, myocarditis (inflammation of heart muscle), as well as nursing mothers. During pregnancy the drug in combination with tireostaticakimi (distressing as the thyroid gland) to counter.Side-EffectsAssociated with potassium iodide-reaction gipercuvstvenosti : skin reactions eozinofilia (increase Eosinophils content in the blood), in very rare cases, shock; Ucaschenne heartbeat, drugs, increased nervousness, insomnia, increased sweating, diarrhea (in patients older than 40 years). The levotirokshinom Snow. levotiroksin.Patient interactionPhenytoin, dikumarin, salicilata, furosemide, klofibrat reinforce effect holestiramin - decreases (decreases resorption). Increases of anticoagulants.OverdosingSymptoms : anxiety, headache, insomnia, tremor, sweating, rapid heartbeat, Aritmii.lechenie : symptomatic therapy.Dosing and AdministrationMinerals are erh, usually within 30 minutes before breakfast and the combination with a small amount of liquid. The initial dose of the drug is 1 / 2 pills a day. After 2-4 weeks dose as necessary, depending on the patient, as well as the body mass index, increased by 1 tablet a day. During pregnancy appoint 1-1 1 / 2 tablets drug per day.Storage conditionstable. : List B. In dry place so that the temperature does not exceed 25 ° CShelf lifetable. : 2 grams.Indications for useTreatment and prevention of endemic goitre diffuse netoksicski goitre (increase in the thyroid gland); Prevention of the recurrence of deaths after the surgical removal (with iodine in the environment).Form ofTablets containing 100 µ g levotiroksina sodium and 130.8 g of potassium iodide, in a package of 50 and 100 pieces. |
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