Aktrapid hm penfill

Roman name

Actrapid HM # # Penfill

The composition and the form of

1 ml solution for injection contains biosinteticeski human insulin 40, or 100 IU; Patients in the 10 ml, in the box one umbrella, or cartridges Penfill 1.5 ml for use with insulin spric-rucka Novopen 1.5 and cartridges Penfill 3 ml for use in spric-ruckah Novopen 3 and Novopen Demi; in blister packaging 5 pcs.

Characteristics

Neutral monokomponennetary human insulin, a short-acting.

Of drugs

Gipoglikemicescoe. Interacts with the specific receptor plazmaticescoy membranes and enters the cell, which activates Tiofat cellular protein stimulates glikiencintetazu, piruvatdegidrogenzu, geksokinazou, ingibiruet lipazu adipose tissue and lipoproteinlipazou. In tandem with the specific receptor facilitates entry of glucose into cells, strengthens its acquisition tissues and promotes the enzyme. Increases Stock glycogen in the muscles, stimulates the synthesis of peptides.

Clinical pharmacology

The effect is 30 minutes after s / to the introduction, reaches its maximum after 1-3 hours and lasts eight hours

Indications

Diabetes mellitus I and II types.

Contraindications

Hypoglycaemia, insulinoma.

Side-Effects

Hypoglycaemia, a breach of refraction (usually at the beginning of therapy), allergic reactions.

Patient interaction

MAO inhibitors, selective beta-adrenoblokatora, ACE inhibitors, salicilata, 25.06.1997, alcohol-added, oral contraceptives, corticosteroids, tireoidnye hormones, tiazidnye dioretiki, simpatomimetiki-weakened gipoglikemiceski effect.

Overdosing

Symptoms : development gipoglikemii (cold sweat, palpitations, tremor, a sense of hunger, excitement, irritability, paleness, headache, drowsiness, and about movements, the speech and vision depression). Heavy gipoglikemii may lead to the temporary or permanent impairment of the brain, coma and death Ishodu.lechenie : sugar, or glucose inside (if the patient is in the minds of), n / a, in the / m or / in-glukagon or / in-glucose.

Precautions

It should be borne in mind that the ability of the car after the people on the human insulin may temporarily decline. The agent can be used, if it is transparent and reading. Using two types of drugs insulin cartridges Penfill need spric-rucka for each type of insulin.

Dosing and Administration

P / to the in / m, / in (using spric-rucki needle should remain under the skin for 6 with, the holding of the press before the full retirement needles from the skin). Feed individually. Introduction 3-6 times a day. Translated patient with vsokoochischennogo porcine insulin on the human dose remains the same, transferring bovine or mixed-its reduced by 10% (except when the initial dose of 0.6 U / kg). Smart Penfill is only designed for individual use.

Storage conditions

r-r d / in. : List B. The temperature of 2-8 ° C (not freezing). Do not store used cartridge in the refrigerator, not to sunlight or extreme temperatur.r-r d / in. : List B. The temperature of 2-8 ° C (not freezing). Do not store used cartridge in the refrigerator, do not expose to sunlight or extreme temperatures.

Shelf life

r-r d / in. : 2.5 city. The cartridge-4 weeks.

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