Aktrapid ms

Roman name

Actrapid # MC

The composition and the form of

1 ml solution for injection contains monokomponentny porcine insulin 40, or 100 IU; Patients in the 10 ml, in the box one bottle.

Characteristics

Neutral monokomponennetary swine short insulin action.

Of drugs

Gipoglikemicescoe. Interacts with the specific receptor plazmaticescoy membranes and enters the cell, which activates Tiofat cellular protein stimulates glikiencintetazu, piruvatdegidrogenzu, geksokinazou, ingibiruet lipazu adipose tissue and lipoproteinlipazou. In tandem with the specific receptor facilitates entry of glucose into cells, strengthens its acquisition tissues and promotes the enzyme. Increases Stock glycogen in the muscles, stimulates the synthesis of peptides.

Clinical pharmacology

The effect is 30 minutes after s / to the introduction, reaches its maximum after 1-3 hours and lasts eight hours

Indications

Diabetes mellitus type I, diabetes mellitus type II (with the resistance guanidine derivatives and sulfonylureas, interkurrentnykh diseases, and operations in the post-period of pregnancy).

Contraindications

Hypoglycaemia, insulinoma.

Side-Effects

Hypoglycaemia (until Tuesday), lipodistrofia (with the long-term use), allergic reaction (skin rash, swelling of the larynx, it is rarely angioneuroticeski swelling, anaphylactic shock).

Patient interaction

MAO inhibitors, selective beta-adrenoblokatora, ACE inhibitors, salicilata, 25.06.1997, alcohol-added, oral contraceptives, corticosteroids, tireoidnye hormones, tiazidnye dioretiki, simpatomimetiki-weakened gipoglikemiceski effect.

Overdosing

Symptoms : development gipoglikemii (cold sweat, palpitations, tremor, a sense of hunger, excitement, irritability, paleness, headache, drowsiness, and about movements, the speech and vision depression). Heavy gipoglikemii may lead to the temporary or permanent impairment of the brain, coma and death Ishodu.lechenie : sugar, or glucose inside (if the patient is in the minds of), n / a, in the / m or / in-glukagon or / in-glucose.

Precautions

Not recommended to use insulinovykh dozatorah with regard to the possibility of precipitation in some kateterh.

Dosing and Administration

P / to the in / in, in / m. Dose is a case-by-case basis. The daily dose of more than 0.6 U / kg, the product should be in the form of two or more users at different locations.

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