Brinsulrapi signs 40 units / ml

Roman name

Brinsulrapi MC 40 IU / ml

The composition and the form of

1 ml solution for injection contains vsokoochischennogo porcine insulin monokomponentny 40 U, as well as 3 mg metarezola as a preservative; in glass bottles to 10 ml, in a cardboard bundle one bottle.

Characteristics

Pork monokomponennetary insulin in a neutral solution. Clear or almost colorless, transparent or nearly transparent liquid.

Of drugs

Gipoglikemicescoe. Lowers the level of glucose in the blood increases its understanding tissues, activates glikogenogenez, synthesis of protein and lipids, down lipolysis, and glikogenoliz making amino acids into glucose.

Clinical pharmacology

The drug produced a rapid and short-acting. The effect is 30 minutes after s / to the introduction, reaches its maximum in the range of 1-3 hours and lasts eight hours

Indications

Diabetes mellitus (type 1) of children and adults, diabetes mellitus (type 2) (in the case of resistance to oral gipoglikemicakim means, including some in the combination therapy; Amidst interkurrentnykh diseases during pregnancy).

Contraindications

Hypersensitivity, hypoglycaemia.

Side-Effects

Hypoglycaemia (paleness of skin, increased sweating, rapid heartbeat, tremor); Allergic reactions (skin rashes, rarely angioneuroticesk 196b7 i swelling, it is rarely anaphylactic shock); Hyperemia, itching, lipodistrofia (with the long-term use) in the injection; Passing of refraction (usually at the beginning of therapy).

Specific guidance

Patients receiving more than 100 U / day Brinsulrapi MCs, in the event of a new drug to госпитализировать.Пе��еход from the same type of insulin on the other should be carried out under the supervision of the level of glucose in Krovi.pri initial appointment, change of insulin, or in the case of the treatment of stress may reduce the ability to drive and mechanisms to other potentially dangerous activities, requiring greater attention and speed Reaktion.pri change the nature and diet, considerable physical loads, infectious diseases, surgical intervention, the occurrence of pregnancy, a violation of the thyroid gland, Addison disease, gipopithuitarizme, renal failure, in patients over 65 years of age must be adjusted Dozu.insulin reduces tolerance to alcohol.

Patient interaction

MAO inhibitors, selective beta-adrenoblokatora, sulfanilamida, 25.06.1997, tetratziklin, klofibrat, cyclophosphamide, fenfluramin, preparations containing ethanol, increased gipoglikemiceski effect; Oral contraceptives, glukokortikoida, tireoidnye hormones, tiazidnye dioretiki, heparin, lithium preparations, Tricyclic antidepressants, weakened. Reserpine and salicilata can both relax, and strengthen gipoglikemicescoe effect.

Overdosing

Symptoms : a sharp increase sweating, rapid heartbeat, tremor, a sense of hunger, causing parestesia to the mouth, lips, headache; In the most severe cases - gipoglikemical Koma.lechenie : ingesting sugar or foods rich in carbohydrates; In the most severe cases, the introduction of glucose (20-40 ml of 40% solution in / in) and glukagona (1 mg in / m).

Dosing and Administration

P / is to determine the dose individually. Solution must enter immediately after entering the syringe. Daily dose of more than 0.6 U / kg should be introduced in the form of two or more users in different areas of the body.

Storage conditions

r-r d / in. : List B. In the dark place at a temperature of 2-8 ° C. Avoid freezing

Shelf life

r-r d / in. : 2.5 g.

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