Insulin zinc suspension (amorphous)

Characteristics

Neutral suspension porcine insulin.

Of drugs

The drugs-gipoglikemicescoe. Lowers the level of glucose in the blood and blood products liver increases glikogenogenez, lipogenez and protein synthesis. Is glucose transport through the cell membrane and its disposal perifericescimi tissues (muscle and adipose tissue), increases the catalytic gexokinaza conducive to the transformation of glucose in glukozo-6-fosfat. Activates glikiencintetazu. Impact of io in patients with diabetes I and II type. Activity begins in 1-2 h after s / to the introduction and reaches its maximum at 5-10 h The effect of 10-16 hours

Indications

Diabetes mellitus type I, diabetes mellitus type II in resistance to oral protivodiabeticski means interkurrentnykh diseases operations pregnancy or poor diet.

Contraindications

Hypersensitivity, hypoglycaemia, insuloma.

Side-Effects

Lipodistrofia, hypoglycaemia incl. gipoglikemical coma and precoma, allergic reactions.

Specific guidance

Forbidden to / in the introduction.

Patient interaction

Effect increase MAO inhibitors, alcohol, selective beta-adrenoblokatora, sulfanilamida, lower-oral contraceptives, glukokortikoida, tireoidnye hormones, tiazidnye dioretiki.

Overdosing

Symptoms : hypoglycaemia, in tajelah cases gipoglikemical Koma.lechenie : appointment of glucose inside, in the case of loss of consciousness, c / to the in / m, / in a glukagona or glucose.

Precautions

Patients receiving a day 100 U or longer, with the replacement of insulin be hospitalized. Relocation of the patient from one dependent on others should be under the control of blood glucose. Dose of insulin to adjust to changes in the nature and diet, high physical activity, infectious diseases, surgery, pregnancy, a violation of the thyroid gland, Addison disease, gipopituitrisme, kidney failure and diabetes among people over the age of 65. In a primary insulin, changing his appearance, or if there is significant physical or mental stresses need to be taken into account to reduce concentration, the speed of mental and motor reactions.

Dosing and Administration

P / to, in the m-1-2 times a day. Doses and the number of injections are individually, depending on the condition of the patient, gravity and the characteristics of the course of the disease and the level of daily glukozurii and Election profile. The daily intake of 0.5-1 U / kg Under dose should not exceed 40 U.

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