Mixtard 30 hm

Roman name

Mixtard # 30 HM

The composition and the form of

1 ml suspension for injection contains biosinteticeski human insulin 100 IU (soluble insulin 30% and izofan-insulin suspension 70%); cartridges Penfill 3 ml for use with insulin spric-rucka Novopen 3 and Novofein needles and cartridges Penfill 1.5 ml for use in spric-ruckah Novopen or Novopen II; in blister packaging 5 pcs. or in the bottle for 10 ml.

Characteristics

Suspension monokomponentny biosinteticeski human insulin bifaznogo action.

Of drugs

Gipoglikemicescoe. Interacts with the specific receptor plazmaticescoy membranes and enters the cell, which activates Tiofat cellular protein stimulates glikiencintetazu, piruvatdegidrogenzu, geksokinazou, ingibiruet lipazu adipose tissue and lipoproteinlipazou. In tandem with the specific receptor facilitates entry of glucose into cells, strengthens its acquisition tissues and promotes the enzyme. Increases Stock glycogen in the muscles, stimulates the synthesis of peptides.

Clinical pharmacology

The effect is 30 minutes after s / to the introduction, reaching a peak in 2-8 hours and lasts 24 hours

Indications

Diabetes mellitus type I, diabetes mellitus type II (with the resistance derivative sulfonylureas, interkurrentnykh diseases, and operations in the post-period of pregnancy).

Contraindications

Hypoglycaemia, insulinoma.

Side-Effects

Allergic reaction; Hypoglycaemia, a breach of refraction (usually at the beginning of therapy).

Specific guidance

The use of the product on the surface of the cartridge Penfill have any damage.

Patient interaction

MAO inhibitors, selective beta-adrenoblokatora, ACE inhibitors, salicilata, 25.06.1997, alcohol-added, oral contraceptives, corticosteroids, tireoidnye hormones, tiazidnye dioretiki, simpatomimetiki-weakened gipoglikemiceski effect.

Overdosing

Symptoms : development gipoglikemii (cold sweat, palpitations, tremor, a sense of hunger, excitement, irritability, paleness, headache, drowsiness, and about movements, the speech and vision depression). Heavy gipoglikemii may lead to the temporary or permanent impairment of the brain, coma and death Ishodu.lechenie : sugar, or glucose inside (if the patient is in the minds of), n / a, in the / m or / in-glukagon or / in-glucose.

Precautions

Smart Penfill is solely for personal use. After injection for a minimum of 6 needle should remain under the skin for the full doses. It should be borne in mind that the ability of the car after the people on the human insulin may temporarily decline. Do not use the drug if mixing suspension becomes homogeneous.

Dosing and Administration

P / to (before the suspension carefully removed before reaching uniformity). And the dose of treatment determine individually. Translated patient with vsokoochischennogo porcine insulin on the human dose not change to the translation from beef or mixed-it is reduced by 10% (except when the total daily dose does not exceed 0.6 U / kg). Daily dose of 0.6 U / kg and above, should be divided into 2-4 injections.

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