Directory → Hormones and their antagonists → Insulins → Monotard mc
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Monotard mcSee also Insulin zinc suspension, compoundRoman nameMonotard # MCThe composition and the form of1 ml suspension for injection contains monokomponentny porcine insulin 40, or 100 IU (zinc suspension-30% amorphous and 70% crystalline); in vials of 10 ml.Of drugsGipoglikemicescoe. Interacts with the specific receptor plazmaticescoy membranes and enters the cell, which activates Tiofat cellular protein stimulates glikiencintetazu, piruvatdegidrogenzu, geksokinazou, ingibiruet lipazu adipose tissue and lipoproteinlipazou. In tandem with the specific receptor facilitates entry of glucose into cells, strengthens its acquisition tissues and promotes the enzyme. Increases Stock glycogen in the muscles, stimulates the synthesis of peptides.Clinical pharmacologyThe effect is a 2.5 h after s / to the introduction, reaching a peak of 15 hours and lasts for 24 hoursIndicationsDiabetes mellitus type I, diabetes mellitus type II (with the resistance derivative sulfonylureas, interkurrentnykh diseases, and operations in the post-period of pregnancy).ContraindicationsHypoglycaemia, insulinoma.Side-EffectsHypoglycaemia, lipodistrofia (with the long-term use), allergic reactions.Patient interactionMAO inhibitors, selective beta-adrenoblokatora, ACE inhibitors, salicilata, 25.06.1997, alcohol-added, oral contraceptives, corticosteroids, tireoidnye hormones, tiazidnye dioretiki, simpatomimetiki-weakened gipoglikemiceski effect.Dosing and AdministrationP / to, the use of a bottle to shake gently. Dose is a case-by-case basis.Storage conditionssusp.d / in. : List B. The temperature of 2-8 ° C (not freezing). The bottle with insulin can be stored at room temperature for up to six weeks.Shelf lifesusp.d / in. : 2.5 g. |
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