Protafan hm

Roman name

Protaphane HM

The composition and the form of

1 ml suspension for injection contains biosinteticeski human insulin 100 IU; cartridges Penfill ® 3 mL for use with insulinovmi spric-ruchkami Novopen ® 3 Novopen ® 3 Demi and Innovo ® and needles Novofein ®; in blister packaging 5 pcs. , in one box packaging.

Characteristics

Monokomponennetary biosinteticeski human izofan-insulin suspension median duration.

Clinical pharmacology

The effect is a 1.5 h after s / to the introduction, is a maximum 12 hours and lasts 24 hours Protafan HM Penfill insulinzawisimom with diabetes used as a bazalnogo insulin combined with insulin short-acting in insulinnezawisimom-both alone, or in combination with the quick insulinami.

Indications

Diabetes mellitus type I, diabetes mellitus type II (with the resistance derivative sulfonylureas, interkurrentnykh diseases, and operations in the post-period of pregnancy).

Contraindications

Hypoglycaemia, insulinoma.

Side-Effects

Gipoglikemicakie condition, allergies lipodistrofia (with the long-term use).

Patient interaction

Gipoglikemiceski effect reinforce acetylsalicylic acid, alcohol, Alpha and beta-adrenoblokatora, amphetamine, 25.06.1997, klofibrat, cyclophosphamide, fenfluramin, fluoxetin, ifosfamid, MAO inhibitors, methyldopa, tetratziklin, tritokvalin, trifosfamid weakening - hlorprotiksen, diazoxid, dioretiki (especially tiazida) glukokortikoida, heparin, hormonal contraceptives, isoniazid, lithium carbonate, nikotinova acid fenotiazina, simpatomimetiki, Tricyclic antidepressants.

Precautions

It should not be a drug if mixing suspension is not fully homogeneous.

Dosing and Administration

P / to, the use of the contents of the cartridge (Protafan HM) gently stirred until a homogeneous suspension. Dose is a case-by-case basis. The transfer of patients from vsokoochischennogo porcine insulin on the human dose not change to the translation from bovine or mixed (swine / butterfly), it reduces by 10% (except in cases where the initial dose of 0.6 U / kg).

Storage conditions

List B. The temperature 2-8 ° C. We expose to sunlight and freeze. The bottle can be stored at room temperature (up to 25 ° C) for 6 weeks.

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