Humulin modification

Roman name

Humulin Regular #

The composition and the form of

Suspension for injection of recombinant human insulin in 1940, or 100 IU / ml; Patients in the 10 ml, or in print on 1.5 and 3.0 ml glucose type Humapen and Bd-pen.

Characteristics

Sterilized solution human insulin.

Of drugs

Represents insulin product identical to the human (pH = 6,6-8,0). Established on the basis of recombinant DNA. Humulin is the exact number of Amino human insulin. Patient short quick action. Home of the drug, after 30 minutes of introduction. Maximum action between the first and third hour.

Clinical pharmacology

The action is over 30 minutes after the maximum, between 1 and 3 h period of 5-7 hours

Indications

Insulinzawisimy diabetes, insulinnezawisimy diabetes, the rapid intervention ketoatsidoze or acute infection in patients with diabetes mellitus.

Contraindications

Hypersensitivity to components of the preparation. Prolongirovanne (long-acting) insulin preparations is not appointed in diabetic coma (loss of consciousness, which is characterized by the complete lack of reaction organism to external stressors, as a result of high levels of blood sugar).

Side-Effects

Allergic reactions in the form of skin rashes, itching, Urticaria; Lipodistrofia (reduced fat); инсулинорезистентнос ть (no response to the introduction of insulin). When expressed as human kidneys, as well as the admission of alcohol may giperglikemicakie reaction (raising blood sugar).

Patient interaction

The need for insulin increases oral contraceptives, corticosteroids, tireoidnye hormones, lower-pill gipoglikemicakie means salicilata, sulfanilamida and drugs.

Dosing and Administration

Doses selected individually, depending on the level of glucose in the blood and urine, of the course of the disease, etc. The dose is less than 40 to 50 U, higher doses used in the low sensitivity to insulino. Introduced subcutaneously. The recommended interval between injection drug admission and write-45-60 min.

Storage conditions

List B. In the dark place (in the original carton) with a temperature of 2 ° C to 8 ° C. Avoid freezing.

Shelf life

r-r d / in. : 2 grams.

Indications for use

Insulinozawisimaya form of diabetes; Giperglikemicescoa coma (loss of consciousness, characterized by the complete lack of reaction organism to external stressors, as a consequence of excessive levels of blood sugar), in the preparation of a patient suffering from diabetes, for the operation; For injuries or acute infections in the patient had diabetes.

Form of

Suspension in vials of 10 ml concentration of 100 U / J Cases (Aktrafan Penfill NM) : Penfill chamber contains 1.5 ml insulin aktrafan NM, the activity of which 100 U in 1 ml tubes for Novo-pen III to 3 ml.

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