Bekotid

Roman name

Becotide

The composition and the form of

Aerosol ingalaii dose-1 dozabeklometazon dose-50 mcgv ingalatore plus metering device with the "option" 200 doses.

Pharmacokinetics

Absorption preparation has been slow. Write mainly in the form of polar metabolites mainly from the faeces (35-76% rate imposed for 96 h), and 14% from urine. In light tissues beklometazon dose Rapidly hydrolyses to beklometazon monpirpionata which, in turn, hydrolyses beklometazon before. The liver also is in the process of turning beklometazon dipropionata in beklometazon monpirpionat and then, polar metabolites.

Clinical pharmacology

Has reduce inflammation and mucous secreting mucus bronchial disorders, reduces the number of fat cells in the mucous lining bronchus is relaxation smooth muscles bronchi. In order to achieve effective results require regular admission. The shows patients who were not previously receiving steroidnuu therapy (or borrowing short courses). Patients receiving steroidnuu therapy, starting with the second week of inhalations, oral steroids gradually abolished.

Indications

Bronchial asthma (including at the same time reducing the effectiveness bronholitikov or combination with kromoglikatom sodium in patients with severe and bronchial asthma), asthma in children.

Pregnancy and lactation

Perhaps, but it should be possible to assess the risk.

Contraindications

Гиперчувствительност ь.

Side-Effects

Osiplosti vote, irritation of mucous membrane throat; Bronhospazm paradoxical, candidiasis mucous membranes of the oral cavity.

Precautions

Patients who are disturbed function crust napochechnikov in stressful situations, the operations, infections, etc. should increase the dosage inhalations and appoint more oral steroids; after oral steroids to reduce the dose inhalations and maintenance level. Therapeutic effect weakened if sprayed cold. As in the application of inhaled corticosteroid, must be especially careful in appointing people active or intensity tuberculosis.

Storage conditions

List B. In the dark place at a temperature of no higher than 30 ° C (not freezing)

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