Directory Hormones and their antagonists Adrenal Glukokortikoida Disodium phosphate
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Disodium phosphate

See also Dexamethasone

Roman name

Dexamethason phosphate

The composition and the form of

1 USD 1 ml injection of dexamethasone phosphate (in the form of 21-digidrofosfata disodium salt), 4 mg; in a box 10 pcs.

Of drugs

Disinfecting, protiwallergicescoe, immunodepressivne, protivosokowoe, desencibilizirutee. Ingibiruet metabolism arahidonova acid suppresses the biosynthesis NG lakotrienov and other mediators of inflammation and allergies.

Indications

Shock different genesis, brain swelling, asthma status, severe allergic reaction (swelling Kwinke, bronhospazm, anaphylacticskie reaction to the drugs, etc.); Rheumatism, kollagenozy, arthritis, degenerative joint diseases, inflammatory diseases of the joints (bursitis, tendowaginit, periartrit, polyarthritis, arthrosis, etc.); Gemoliticaskie acute anaemia, thrombocytopenia, chlamydia, agranulozitos, heavy infections (in combination with antibiotics) napochechnikovaya acute malnutrition (in combination with �инералокортикоидами) .

Contraindications

Pepticalkie stomach ulcer expressed osteoporosis, psychosis, viral infections, fatigue eye disease, the active form of tuberculosis, amebnye infection, systemic mikozy, infant cerebral palsy, glaucoma, the year (8 weeks), and after (2 weeks) inoculation.

Side-Effects

When short-term therapy (up to 10 days), gastrointestinal bleeding, reduced immunity, reduce tolerance to glukoze. With long-term therapy-syndrome Itsenko - Kushinga. In the injection-aseptic bone necrosis (in the area of the femur, the head of the humerus), abscesses, infection, pain. Allergic reactions, skin person.

Precautions

Be wary appointed to the concerns of hypertension, diabetes, gipotireoze, cirrhosis of the liver; With great caution, with the pregnancy (particularly in the first trimester), children (in the long-term care necessary to monitor the dynamics of growth and development). At the time of treatment lactoirutm women should give up breast-feeding. In infectious diseases appointed in the face of antibiotics. To avoid the syndrome treatment out gradually.

Dosing and Administration

In / in, in / m, intra-and periartikulyarno. Doses set individually, depending on the type and severity of the disease and on the sensitivity of the patient. Recommended dosage : when in / in and / m for a therapy systemic diseases on 0.2-20 mg; The treatment of the joints (or periartikulyarnoe endoprothesis a) for the 2-8 mg.

Storage conditions

r-r d / in. : List B.

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