Directory → Hormones and their antagonists → Adrenal → Glukokortikoida → Dexazon
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DexazonSee also DexamethasoneRoman nameDexasonThe composition and the form of1 tablet contains dexamethasone 0.5 mg; Patients in the 50 st.1 USD 1 ml solution for injection-dexamethasone (in the form of sodium phosphate), 4 mg; in a carton 5 or 25 pcs.Of drugsDisinfecting, immunomodulirutee. Induces synthesis and secretion lipomodulina, inhibiting fosfolipazu A_2 hampered education metabolites arahidonova acid (GHG LT, Tha_2, FAT); From Ige interaction with the receptor fat cells and bazofilov and activation of complement, oppressing exudation.IndicationsPrimary adrenakorticalnaya deficiency, congenital gipoplasia napochechnikov, tireoidit; Psoriaticeski arthritis, brahialgia, systemic lupus red, acute revmocardit; Puzarchaty gerpeticeski dermatitis, erythema multiformnaya, dermatitis (exfoliativei, atopic), diffuse sclerit, ekstrabulbarnyi myofasciitis inflammation visual stimulus; Sarkoidoz, berillios, Leffler syndrome, disseminated tuberculosis; Trombozitopenica idiopathic purpura, thrombocytopenia, eritroblastopenia, gipoplastical congenital anaemia, or idiopathic Autoimmune disease; Lymphoblastic, lymphoma and Hodgkin lymphoma, plazmotsytoma; principally with the syndrome uremyei, idiopathic jade; Ulcerative Colitis, hepatitis; TB meningitis with subarhanoidalna blockade trihinoz involving central nervous system or heart. brain edema, a swelling of light detected adrenakorticalna functions.ContraindicationsRelative : systemic fungal infections, peptica ulcers, depression, diabetes mellitus, ophthalmic herpes simple cornea female heart failure, the syndrome Itsenko - Kushinga, osteoporosis, apnoea condition pregnancy.Side-EffectsDelay sodium and water, the loss of potassium alkaloz, hypertension, male, miopatia, osteoporosis, fractures, shock syndrome (peptical me with the possibility of leather and bleeding, pancreatitis, Ulcerative ezofagit), convulsions, dizziness, headache, exofthalm, raising vnutriglaznogo pressure back podkapsuliarnaya cataracts, menstrual irregularities, fatigue Itsenko - Kushinga, reduced tolerance to carbohydrates, stunting, thinning and vulnerable skin, facial erythema, skin, reducing skin sensitivity.PrecautionsFor patients with the risk of thrombosis should take medicine at the same time as antikoagulyantami, older patients with osteoporosis from anabolikami. Children are encouraged therapy intermittently. Lactoirute women at the time of treatment should stop breastfeeding.Dosing and AdministrationAnswers : inwards morning, the initial dose, 12 mg per day; With the therapeutic effect dose gradually reduced to the level of the minimum support; Treatment ceased gradually. Injections : with the / m and / with a daily dose ranging from 4 to 80 mg per day until a satisfactory effect (then continue therapy with the help of pills); Vnutrisustavnogo to use : large joints, 2-4 mg, small, 0.8-1 mg; Dose for the vnutribruchinnogo - 2-3 mg.Storage conditionsr-r d / in. : List B. In the dark place at a temperature below 25 ° Ctabl. : List B. The temperature of 15-30 ° CShelf lifer-r d / in. : 3 g.tabl. : 5 years |
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